Results 121 to 130 of about 31,146 (236)

Perioperative Cardioprotection: General Mechanisms and Pharmacological Approaches

, 2020
Cardioprotection encompasses a variety of strategies protecting the heart against myocardial injury that occurs during and after inadequate blood supply to the heart during myocardial infarction.
Hollmann, Markus W., Raupach, Annika, Huhn, Ragnar, Torregroza, Carolin, Feige, Katharina, Weber, Nina C.   +5 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, Volume 16, Issue 10, Page 1958-1973, October 2026.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Colombiains A–C, Three New Alkaloids From the Soft Coral‐Derived Fungus Cladosporium colombiae CSGL 10M10

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Three new alkaloids, colombiains A–C (1–3), together with eight known ones (4–11) were isolated from the soft coral‐derived fungus Cladosporium colombiae CSGL 10M10. Compounds 6 and 11 exhibited significant cardioprotective activity against OGD/R‐induced injury in H9c2 cardiomyocytes at 10 µM.
Jing Xie, Bing‐Bing Liu, Yang‐Ying Zheng, Jun‐Feng Huan, Xiao‐Yu Tian, Xiu‐Ping Lin, Hui‐Mei Xie, Yuan‐Yuan Cheng, Cui‐Xian Zhang   +8 more
wiley   +1 more source

Chaîne respiratoire et pore de transition de perméabilité mitochondriale dans la cardioprotection

, 2009
The mitochondrial permeability transition pore (mPTP) plays an important role in cell death and cardioprotection. Our hypothesis is that the complex I of mitochondrial respiratory chain regulates the opening of mPTP.
Li, Bo
core   +1 more source

Amyloid‐Forming Amylin Secreted by the Pancreas Promotes Hypoxia‐Inducible Factor Activation and Mitochondrial Alterations in Liver and Heart During Type 2 Diabetes Pathogenesis

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Human amylin is secreted from the pancreas of HIP rats and is amyloidogenic, forming aggregates systemically. In comparison with age‐matched control (WT), hyperglycemic (UCD) and amylin knockout rats (AKO), HIP rats showed increased hypoxia‐inducible factors (HIF‐1/2) in heart and liver, alongside alterations in mitochondrial electron transfer system ...
Alice E. Knapton, Nirmal Verma, Deepak Kotiya, Alice P. Sowton, Benjamin D. Thackray, Lorenz M. W. Holzner, Paula M. Darwin, Sanda Despa, Florin Despa, Andrew J. Murray   +9 more
wiley   +1 more source

Plant‐Derived Polyphenol Salvianolic Acid B Attenuates Cardiomyocyte Pyroptosis by Modulating the MMP12–NLRP3 Signaling Axis

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
HG induces MMP12 upregulation in AC16 cardiomyocytes, which activates the NLRP3 inflammasome, triggers GSDMD‐mediated pyroptosis, and promotes the release of inflammatory cytokines. Sal B alleviates cardiomyocyte damage by modulating MMP12, while MMP12 overexpression abrogates this protective effect.
Zilong Xie, Zhi‐Kai Yang, Longhui Zheng, Pinghua Wu, Shengxian Chen, Xiaotong Ye, Yi Gao   +6 more
wiley   +1 more source

Effects of Rho Kinase Inhibition on Cardioprotection

, 2005
Rho Kinase (Rho-K) has been implicated in the pathophysiology of many deleterious conditions and its inhibition was shown to ameliorate these compromising effects.
Thomas, Christopher Scott
core   +1 more source

Harnessing Terminalia arjuna in Next Generation Phytomedicine: Cutting Edge Nutraceutical Trends Shaping Food and Health

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
This graphical abstract illustrates the complete translational pipeline of Terminalia arjuna in modern phytomedicine and functional food development. It is rich in key bioactive compounds like arjunolic acid, arjungenin, flavonoids, and tannins which serve as the foundation for the plant's versatile medicinal uses and offers broad therapeutic benefits ...
Ishani Banerjee, Fahika Nazeerulla, Manash Kumar Paul, Sujit Kumar Bhutia, Deblina Basu, Subhadip Mukhopadhyay   +5 more
wiley   +1 more source

Cardioprotection with halogenated gases: how does it occur?

, 2017
Jose Luis Guerrero-Orriach,1–3 Juan Jose Escalona Belmonte,1 Alicia Ramirez Fernandez,1 Marta Ramirez Aliaga,1 Manuel Rubio Navarro,1 Jose Cruz Mañas1 1Department of Cardioanesthesiology, Virgen de la Victoria University Hospital ...
Ramirez Aliaga M, Escalona Belmonte JJ, Ramirez Fernandez A, Guerrero-Orriach JL, Rubio Navarro M, Cruz Mañas J   +5 more
core  

Elucidation of the Molecular Mechanisms of Electrically-Induced Cardioprotection [PDF]

, 2019
Cardiovascular disease is the leading cause of death worldwide. A myocardial infarction (MI), commonly known as a heart attack, is a major event in cardiovascular disease characterized by reduced blood flow to the heart. The ischemia and reperfusion (I/R)
Roessler, Anne Elizabeth
core   +1 more source