Results 101 to 110 of about 61,690 (282)

Transfusion of blood products to neonatal and pediatric extracorporeal membrane oxygenation patients: A prospective, observational study

open access: yesTransfusion, EarlyView.
Abstract Study Question To describe the blood product utilization during neonatal and pediatric extracorporeal membrane oxygenation (ECMO) and to determine whether its usage correlates with clinical outcomes of bleeding, thrombosis or mortality. Design Prospective observational study of neonatal and pediatric ECMO patients from September 2016, until ...
Rebecca Barton   +15 more
wiley   +1 more source

Red blood cells stored in anticoagulant versus additive solution for large volume transfusions in pediatric patients undergoing cardiopulmonary bypass

open access: yesTransfusion, EarlyView.
Abstract Background The safety of red blood cells (RBCs) in additive solutions (AS) for large‐volume transfusion (LVT) in pediatrics remains understudied. This study examines the laboratory and clinical impact of CPD‐stored products versus CP2D/AS‐3 products in pediatric patients receiving LVT during cardiac surgery.
Nabiha H. Saifee, Meghan Delaney
wiley   +1 more source

The role of microglia in Neuroinflammation associated with cardiopulmonary bypass

open access: yesFrontiers in Cellular Neuroscience
Cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) are indispensable core techniques in cardiac surgery. Numerous studies have shown that cardiopulmonary bypass and deep hypothermic circulatory arrest are associated with the ...
Lingda Meng   +4 more
doaj   +1 more source

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

open access: yesExperimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris   +10 more
wiley   +1 more source

Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes

open access: yesExperimental Physiology, EarlyView.
Abstract Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is associated with significant morbidity, mortality and healthcare utilization. Catheter ablation is increasingly used as a rhythm‐control intervention for patients with symptomatic paroxysmal and persistent AF, yet recurrence rates remain suboptimal.
Konstantinos Grigoriou   +11 more
wiley   +1 more source

Genetically predicted waist circumference and risk of atrial fibrillation

open access: yesChinese Medical Journal
. Introduction:. Observational studies have revealed an association between waist circumference (WC) and atrial fibrillation (AF). However, it is difficult to infer a causal relationship from observational studies because the observed associations could
Wenting Wang   +11 more
doaj   +1 more source

The interplay between pulsatility, sympathetic regulation and renal physiology: Implications for left ventricular assist devices

open access: yesExperimental Physiology, EarlyView.
Abstract Left ventricular assist devices have gained traction both as a bridge therapy and as a destination therapy in the management of heart failure. Many of these devices reinstate blood flow in a continuous manner as opposed to the pulsatile flow present in normal physiology.
Tania Warnakulasuriya   +2 more
wiley   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone   +1 more
wiley   +1 more source

Emergency Use of Cardiopulmonary Bypass

open access: yesJournal of Interventional Cardiology, 1995
Emergency cardiopulmonary support has been used in the United States since 1986. Physicians at participating centers for the National Registry of Elective Supported Angioplasty have contributed data on emergent cardiopulmonary support from their institutions.
openaire   +2 more sources

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 2, Page 557-567, August 2026.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon   +5 more
wiley   +1 more source

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