Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Air or 100% oxygen for asphyxiated babies? Time to decide
Both experimental and clinical studies have demonstrated that room air is as efficient as 100% oxygen for newborn resuscitation and improves short-term recovery.
Robertson, NJ
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Chinese Society of Pediatric Anesthesiology Guideline for Pediatric Sedation (2025)
ABSTRACT Background With the increasing variety of pediatric diagnostic procedures, a growing number of children require sedation for diagnostic examinations. Appropriate sedation protocols guarantee the safety of children during sedation and improve its efficiency.
Xingrong Song +39 more
wiley +1 more source
Cardiopulmonary arrest and cardiopulmonary resuscitation in pregnancy Number 3 - 2026. [PDF]
Alves ÁLL, da Silva LB, Knobel R.
europepmc +1 more source
This review evaluates the clinical potential and limitations of intranasal (IN) drug administration in veterinary anaesthesia and emergency care. IN delivery can provide clinically relevant sedation, analgesia and drug reversal, but its success is not universally reliable and is strongly influenced by species‐specific anatomy, formulation ...
Majid Jafarbeglou
wiley +1 more source
Impact of Cardiopulmonary Resuscitation Health Care Workers' Physical Health Parameters on Cardiopulmonary Resuscitation Performance Quality in Simulated Manikin-Based Settings-A Systematic Review. [PDF]
Prakash P +6 more
europepmc +1 more source
The feasibility of performing a randomised controlled trial of therapeutic hypothermia for neuroprotection after paediatric cardiac arrest in the UK [PDF]
Cardiac arrest in paediatric patients often results in death or survival with severe brain injury. Therapeutic hypothermia, lowering of core body temperature to 32 to 34⁰C may reduce injury to the brain in the period after circulation has been restored.
Scholefield, Barnaby R.
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ABSTRACT Background Early‐onset pneumonia is a possible complication after out‐of‐hospital cardiac arrest (OHCA) resuscitation. Whether or not a suspected aspiration during prehospital care is associated with the development of early‐onset pneumonia has not been studied.
Karoliina Yli‐Luukko +4 more
wiley +1 more source
The use of supplemental oxygen during cardiopulmonary resuscitation - a systematic review of the literature. [PDF]
Skrifvars MB +18 more
europepmc +1 more source
Pediatric Resuscitation: Evaluation of a Clinical Curriculum
Objective: To assess the impact of a 6-hour pediatric resuscitation curriculum on the comfort levels of resident physicians’ evaluation and treatment of critically ill pediatric patients. Methods: An evaluation instrument assessed resident comfort levels,
Nagel , PhD, Rollin +2 more
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