Results 11 to 20 of about 121,809 (276)

Complications of cardiopulmonary resuscitation in non-traumatic cases and factors affecting complications [PDF]

open access: yesEgyptian Journal of Forensic Sciences, 2016
In this study, bodily injuries related to chest compression were examined in non-traumatic death cases that underwent autopsy. This study aimed to evaluate factors that can affect these injuries.
Umit Kaldırım   +6 more
doaj   +3 more sources

Pyk2 regulates sepsis-induced lung injury via ferroptosis [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Objective(s): The onset of sepsis represents a hyper-inflammatory condition that can lead to organ failure and mortality. Recent findings suggest a potential beneficial effect of protein tyrosine kinase Pyk2 inhibitor on sepsis in a mouse model.
Jia Wang, Pengtao Bao, Yugeng Liu
doaj   +1 more source

Effect of Fluid Resuscitation Strategies for Obese Patients with Sepsis and Septic Shock: A Systematic Review

open access: yesIntensive Care Research, 2022
Purpose As the Surviving Sepsis Campaign (2021) recommended, patients with sepsis should be given a liquid infusion of 30 ml/kg (ideal body weight). However, the strategy may result in insufficient resuscitation for obese patients with sepsis. Therefore,
Yijun Zhang   +3 more
doaj   +1 more source

MK-886 protects against cardiac ischaemia/reperfusion injury by activating proteasome-Keap1-NRF2 signalling

open access: yesRedox Biology, 2023
Oxidative stress is considered a key factor contributing to the initiation and development of cardiac injury following ischaemia‒reperfusion (I/R). Arachidonate 5-lipoxygenase (ALOX5) is a rate-limiting enzyme for leukotriene biosynthesis.
Kai-Na Shi   +4 more
doaj   +1 more source

Time Series Transcriptomic Analysis by RNA Sequencing Reveals a Key Role of PI3K in Sepsis-Induced Myocardial Injury in Mice

open access: yesFrontiers in Physiology, 2022
Septic cardiomyopathy is the main complication and cause of death of severe sepsis with limited therapeutic strategy. However, the molecular mechanism of sepsis-induced cardiac injury remains unclear.
Xiao Yan   +6 more
doaj   +1 more source

RETRACTED: Artificial intelligence for emergency medical care

open access: yesHealth Care Science, EarlyView., 2023
‘Applications of artificial intelligence in emergency medical service’. Abstract There is increasing research into the potential benefits of incorporating artificial intelligence (AI) and machine learning algorithms into emergency medical services. AI is finding new applications across a wide range of sectors, one of which is healthcare, where it is ...
Shivam Rajput   +2 more
wiley   +1 more source

Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy

open access: yesFrontiers in Pharmacology, 2021
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis-induced circulatory and cardiac dysfunction is associated with high mortality rates.
Wenqing Ji   +11 more
doaj   +1 more source

Sodium–Glucose Co-Transporter 2 Inhibition With Empagliflozin Improves Cardiac Function After Cardiac Arrest in Rats by Enhancing Mitochondrial Energy Metabolism

open access: yesFrontiers in Pharmacology, 2021
Empagliflozin is a newly developed antidiabetic drug to reduce hyperglycaemia by highly selective inhibition of sodium–glucose co-transporter 2. Hyperglycaemia is commonly seen in patients after cardiac arrest (CA) and is associated with worse outcomes ...
Yunke Tan   +21 more
doaj   +1 more source

Protective effect of canagliflozin on post-resuscitation myocardial function in a rat model of cardiac arrest

open access: yesIntensive Care Medicine Experimental, 2023
Background Currently, most patients with cardiac arrest (CA) show reversible myocardial dysfunction, hemodynamic instability, systemic inflammation and other pathophysiological state in early stage of resuscitation, some patients may eventually progress ...
Tianfeng Hua   +7 more
doaj   +1 more source

Early human albumin administration is associated with reduced mortality in septic shock patients with acute respiratory distress syndrome: A retrospective study from the MIMIC-III database

open access: yesFrontiers in Physiology, 2023
Background: Sepsis-induced acute respiratory distress syndrome (ARDS) was associated with higher mortality. It is unclear whether albumin supplementation early in the course of ARDS can affect the prognostic outcomes of septic shock (SS) patients with ...
Xiya Wang   +13 more
doaj   +1 more source

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