Results 41 to 50 of about 171,368 (249)

Psmb8 inhibits mitochondrial fission and alleviates myocardial ischaemia/reperfusion injury by targeting Drp1 degradation

Cell Death and Disease
The mitochondrial dynamic imbalance is an important cause of myocardial ischaemia/reperfusion (I/R) injury and dysfunction. Psmb8, as one of the immunoproteasome catalytic subunits, is a key regulator of protein homoeostasis, inflammation and some ...
Hui-Xiang Su, Luo-Luo Xu, Pang-Bo Li, Hai-Lian Bi, Wen-Xi Jiang, Hui-Hua Li   +5 more
doaj   +1 more source

Outpatient preoperative parenteral nutrition in malnourished surgical patients: A feasibility study (the OPPORTUNITY study)

Nutrition in Clinical Practice, EarlyView.
Abstract Preoperative parenteral nutrition (PN) improves outcomes in malnourished surgical patients. Traditionally, this requires hospital admission, increasing length of stay and costs—challenges worsened by limited hospital bed availability. Outpatient PN may offer a feasible alternative.
Narisorn Lakananurak, Leah Gramlich
wiley   +1 more source

The impact of cardiopulmonary resuscitation (CPR) training on schoolchildren and their CPR knowledge, attitudes toward CPR, and willingness to help others and to perform CPR: mixed methods research design

BMC Public Health, 2020
Background The benefits of cardiopulmonary resuscitation training for schoolchildren are well known, but the appropriate age for introducing training is still being discussed.
Sanela Pivač, Primož Gradišek, Brigita Skela-Savič   +2 more
doaj   +1 more source

Factors Influencing Secondary Traumatic Stress in Pediatric Nurses: An Integrative Review

Research in Nursing &Health, EarlyView.
ABSTRACT Secondary traumatic stress is a significant occupational concern in pediatric nursing because frequent exposure to traumatic events can compromise nurses' emotional health, increase burnout, and reduce the quality of care. The aim of this integrative review is to synthesize the current evidence on the prevalence and contributing factors of ...
Heemoon Lim, Won Jin Seo, Hyejung Lee
wiley   +1 more source

Prehospital randomised assessment of a mechanical compression device in cardiac arrest (PaRAMeDIC) trial protocol [PDF]

, 2010
Background Survival after out-of-hospital cardiac arrest is closely linked to the quality of CPR, but in real life, resuscitation during pre-hospital care and ambulance transport is often suboptimal.
Matthew W Cooke, Cooke, MW, Slowther, A, Quinn, Tom, Deakin, Charles D., Lamb, Sarah E, Jessica Horton, Woollard, M, Lall, Ranjit, McCabe, Chris, Deakin, C, Perkins, Gavin D., Gates, S, Tom Quinn, Lamb, S. E., Chris McCabe, Slowther, Anne, McCabe, Christopher, Perkins, GD, Horton, J, Perkins, Gavin, Lall, R, Malcolm Woollard, Cooke, Matthew W, Anne Slowther, Woollard, Malcolm, Cooke, Matthew, Gates, Simon, Lamb, Sarah, Charles Deakin, Sarah E Lamb, Gavin D Perkins, Perkins, Gavin D, Simon Gates, Deakin, Charles, Horton, Jessica, McCabe, C, Quinn, T, Ranjit Lall, Lamb, SE   +39 more
core   +2 more sources

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Metabolomic biomarker differences of sarcopenia in older patients with sepsis

Frontiers in Medicine
BackgroundSarcopenia has a high incidence in older patients with sepsis and is closely associated with poor prognosis, but its metabolic characteristics under this specific stress state remain unclear.
Yiyang Liu, Yiyang Liu, Tianren He, Tianren He, Siyu Chen, Siyu Chen, Ziyi Li, Ziyi Li, Xue Mei, Xue Mei, Xinhua He, Xinhua He, Na Shang, Na Shang   +13 more
doaj   +1 more source

Accidental plant poisonings in France: Lessons from a decade of national toxicovigilance

PLANTS, PEOPLE, PLANET, EarlyView.
Accidental plant poisonings reveal how modern societies are losing everyday botanical knowledge once central to food and health safety. By analyzing a decade of French toxicovigilance data, this study shows that most severe cases arise from plant misidentification or misguided self‐medication.
Gaël Le Roux, Adrien Maillot, Sylvie Michel, Jérôme Langrand, Sébastien Larréché, Christine Tournoud, David Boels, Magali Labadie, Nicolas Delcourt, Nathalie Paret, Luc de Haro, Sandra Sinno‐Tellier   +11 more
wiley   +1 more source

Association between statins use and mortality in critically ill patients with sepsis included myocardial injury: a retrospective cohort study

European Journal of Medical Research
Background The treatment of patients with sepsis included myocardial injury (SIMI) remains a subject of debate. Given the pharmacological effects of statins in both sepsis and cardiovascular disease, this study aimed to investigate the association ...
Shuxing Wei, Yiming Dong, Yanqian Su, Ying Chen, Xiya Wang, Hongmeng Dong, Danlei Weng, Yue Hu, Shubin Guo, Xue Mei, Wenqing Ji   +10 more
doaj   +1 more source

Knowledge of non-healthcare individuals towards cardiopulmonary resuscitation: a cross-sectional study in Riyadh City, Saudi Arabia

International Journal of Emergency Medicine, 2021
Background Most sudden cardiac arrests occur at home, with low rates of bystander cardiopulmonary resuscitation being performed. We aimed to assess knowledge of cardiopulmonary resuscitation among individuals in Riyadh City, Saudi Arabia, who are not ...
Reema M. Alhussein, Mansoor M. Albarrak, Abdulaziz A. Alrabiah, Nawfal A. Aljerian, Hashim M. Bin Salleeh, Ahmad S. Hersi, Tariq A. Wani, Zohair A. Al Aseri   +7 more
doaj   +1 more source