Results 11 to 20 of about 69,034 (308)

Cardiopulmonary resuscitation in low-resource settings: a statement by the International Liaison Committee on Resuscitation, supported by the AFEM, EUSEM, IFEM, and IFRC [PDF]

open access: yes, 2023
Most recommendations on cardiopulmonary resuscitation were developed from the perspective of high-resource settings with the aim of applying them in these settings.
Baig, Noor   +14 more
core   +4 more sources

Cardiopulmonary Resuscitation

open access: yesCritical Care Clinics
Here we describe the evidence for point-of-care ultrasonography application in cardiac arrest. Most commonly, transthoracic echocardiography and transesophageal echocardiography imaging may identify reversible etiologies for arrest, guide chest compression quality, and provide prognostic information. Many arrest ultrasound protocols have been described,
Goyal A, Singh B, Patel PH.
europepmc   +3 more sources

Effect of Fluid Resuscitation Strategies for Obese Patients with Sepsis and Septic Shock: A Systematic Review

open access: yesIntensive Care Research, 2022
Purpose As the Surviving Sepsis Campaign (2021) recommended, patients with sepsis should be given a liquid infusion of 30 ml/kg (ideal body weight). However, the strategy may result in insufficient resuscitation for obese patients with sepsis. Therefore,
Yijun Zhang   +3 more
doaj   +1 more source

MK-886 protects against cardiac ischaemia/reperfusion injury by activating proteasome-Keap1-NRF2 signalling

open access: yesRedox Biology, 2023
Oxidative stress is considered a key factor contributing to the initiation and development of cardiac injury following ischaemia‒reperfusion (I/R). Arachidonate 5-lipoxygenase (ALOX5) is a rate-limiting enzyme for leukotriene biosynthesis.
Kai-Na Shi   +4 more
doaj   +1 more source

Pyk2 regulates sepsis-induced lung injury via ferroptosis [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Objective(s): The onset of sepsis represents a hyper-inflammatory condition that can lead to organ failure and mortality. Recent findings suggest a potential beneficial effect of protein tyrosine kinase Pyk2 inhibitor on sepsis in a mouse model.
Jia Wang, Pengtao Bao, Yugeng Liu
doaj   +1 more source

Time Series Transcriptomic Analysis by RNA Sequencing Reveals a Key Role of PI3K in Sepsis-Induced Myocardial Injury in Mice

open access: yesFrontiers in Physiology, 2022
Septic cardiomyopathy is the main complication and cause of death of severe sepsis with limited therapeutic strategy. However, the molecular mechanism of sepsis-induced cardiac injury remains unclear.
Xiao Yan   +6 more
doaj   +1 more source

Aldehyde Dehydrogenase 2 Protects Against Lipopolysaccharide-Induced Myocardial Injury by Suppressing Mitophagy

open access: yesFrontiers in Pharmacology, 2021
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis-induced circulatory and cardiac dysfunction is associated with high mortality rates.
Wenqing Ji   +11 more
doaj   +1 more source

Protective effect of canagliflozin on post-resuscitation myocardial function in a rat model of cardiac arrest

open access: yesIntensive Care Medicine Experimental, 2023
Background Currently, most patients with cardiac arrest (CA) show reversible myocardial dysfunction, hemodynamic instability, systemic inflammation and other pathophysiological state in early stage of resuscitation, some patients may eventually progress ...
Tianfeng Hua   +7 more
doaj   +1 more source

Sodium–Glucose Co-Transporter 2 Inhibition With Empagliflozin Improves Cardiac Function After Cardiac Arrest in Rats by Enhancing Mitochondrial Energy Metabolism

open access: yesFrontiers in Pharmacology, 2021
Empagliflozin is a newly developed antidiabetic drug to reduce hyperglycaemia by highly selective inhibition of sodium–glucose co-transporter 2. Hyperglycaemia is commonly seen in patients after cardiac arrest (CA) and is associated with worse outcomes ...
Yunke Tan   +21 more
doaj   +1 more source

Cardiopulmonary resuscitation

open access: yesMedicine, 2022
Performing cardiopulmonary resuscitation is a key competency for healthcare professionals. Training in immediate and advanced life support is a requirement for UK doctors; this is depicted in the Foundation training programme competencies and in the Internal Medicine Training curriculum.
Mitropoulou, Panagiota   +1 more
openaire   +2 more sources

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