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Treatment of Cardiorenal Syndrome
Cardiology Clinics, 2019The treatment of cardiorenal syndrome is as complex as the various mechanisms underlying its pathophysiology. Randomized controlled data typically focus on the treatment of heart failure with cardiac specific endpoints and a lack of worsening renal function used as a surrogate for efficacy. When heart failure is considered the inciting event, the acute
Jack, Rubinstein, Darek, Sanford
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Biomarkers of cardiorenal syndrome
Annales de biologie clinique, 2013Complex interactions existing between cardiac and renal diseases led to define 5 types of so-called cardiorenal syndromes. This classification is based on the organ primarily involved and the acute or chronic failure. The mutual impact of renal and cardiac functions makes it difficult to evaluate and manage patients with cardiorenal syndromes and ...
Nils, Kuster +7 more
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Biomarkers in Cardiorenal Syndrome
Blood Purification, 2014Cardiac and renal diseases often coexist. Treatment may prove difficult as early diagnosis and effective therapy may be hindered by a lack of robust markers of disease activity. However, several candidate molecules are now available which may help elucidate the complexities of organ cross-talk, enabling effective therapies.
Lui G, Forni, Lakhmir S, Chawla
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Epidemiology of Cardiorenal Syndromes
2010Cardiac and kidney disease are common, increasingly encountered and frequently coexist. A consensus classification for the cardiorenal syndrome (CRS) and its specific subtypes has been developed by the Acute Dialysis Quality Initiative (ADQI). The five CRS subtypes have a similar underlying pathophysiology, however they likely have distinguishing ...
Sean M, Bagshaw, Dinna N, Cruz
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Biomarkers and physiopathology in the cardiorenal syndrome
Clinica Chimica Acta, 2015Acute cardiorenal syndrome (CRS) corresponds to an association of acute heart failure and a worsening of renal function. The detection of acute kidney injury (AKI) unfortunately occurs at a late stage of CRS, leading to an increased mortality of the patients.
BOUQUEGNEAU, Antoine +3 more
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Cardiorenal Syndrome in Critical Care: The Acute Cardiorenal and Renocardiac Syndromes
Advances in Chronic Kidney Disease, 2013Heart and kidney disease often coexist in the same patient, and observational studies have shown that cardiac disease can directly contribute to worsening kidney function and vice versa. Cardiorenal syndrome (CRS) is defined as a complex pathophysiological disorder of the heart and the kidneys in which acute or chronic dysfunction in one organ may ...
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Prevention of Cardiorenal Syndromes
2010The cardiorenal syndromes (CRS) are composed of five recently defined syndromes which represent common clinical scenarios in which both the heart and the kidney are involved in a bidirectional injury process leading to dysfunction of both organs. Common to each subtype are multiple complex pathogenic factors, a precipitous decline in function and a ...
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Congestion and Cardiorenal Syndromes
2010Acute right ventricular failure is increasingly seen in the emergency room and intensive care unit. Acute right ventricular failure is associated with high central venous pressure (CVP) and altered liver and kidney enzymes. Several studies suggested that high CVP might markedly reduce renal blood flow by increasing renal backpressure.
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