Results 81 to 90 of about 15,796 (188)
Abstract Aims To evaluate the effectiveness of combination therapy with sodium‐glucose cotransporter 2 (SGLT‐2) inhibitors and glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) compared with continued SGLT‐2 inhibitor therapy in routine practice among individuals with type 2 diabetes.
Gregor A. Maier +3 more
wiley +1 more source
Cardiorenal Syndrome in Acute Heart Failure Syndromes
Impaired cardiac function leads to activation of the neurohumoral axis, sodium and water retention, congestion and ultimately impaired kidney function. This sequence of events has been termed the Cardiorenal Syndrome.
Mohammad Sarraf, Robert W. Schrier
doaj +1 more source
Cardiorenal Syndrome Type 4—Cardiovascular Disease in Patients with Chronic Kidney Disease: Epidemiology, Pathogenesis, and Management [PDF]
The term cardiorenal syndrome refers to the interaction between the heart and the kidney in disease and encompasses five distinct types according to the initial site affected and the acute or chronic nature of the injury.
Panagiotis Pateinakis +1 more
core +1 more source
Abstract Aims Real‐world medication use varies across clinical trial and healthcare settings; therefore, we evaluated GLP‐1 receptor agonist (GLP‐1RA) persistence and dose titration among adults with type 2 diabetes in UK primary care, stratified by agent, obesity status, cardiovascular disease (CVD) history, and sex assigned at birth.
Franziska S. Ulrich +3 more
wiley +1 more source
A simple prognostic index in acute heart failure [PDF]
Background Rapid effective triage is integral to emergency care in patients hospitalized for heart failure, to guide the type and intensity of therapy.
Cristina MOLLICA +3 more
core +1 more source
Abstract Pulmonary hypertension (PH) is a severe vascular complication of sickle cell disease (SCD); yet, not all patients with SCD develop PH, and PH also arises independently. This duality underscores the need to understand their intersecting biology.
Francesca I. Cendali +22 more
wiley +1 more source
Improving Prognosis Estimation in Patients with Heart Failure and the Cardiorenal Syndrome
The coexistence of heart failure and renal dysfunction constitutes the “cardiorenal syndrome” which is increasingly recognized as a marker of poor prognosis.
Husam M. Abdel-Qadir +2 more
doaj +1 more source
ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This review aims to provide a comprehensive overview of LEO's pharmacokinetics, pharmacological mechanisms ...
Zhouyue Gu
wiley +1 more source
Síndrome cardiorrenal na insuficiência cardíaca aguda: um círculo vicioso?
Resumo: Introdução e objetivos: O valor prognóstico da deterioração da função renal é indiscutível nos doentes com insuficiência cardíaca aguda. No contexto nacional sabe‐se pouco acerca do peso relativo da síndrome cardiorrenal no internamento destes ...
Francisca Caetano +6 more
doaj +1 more source
Abstract Objective Recently, the American Heart Association defined, staged, and highlighted the multisystem consequences of poor cardiovascular‐kidney‐metabolic (CKM) syndrome health with a clarion call to harmonize guidelines and provide opportunities for actionable preventive interventions before overt CVD.
Eric K. Broni +5 more
wiley +1 more source

