Results 121 to 130 of about 64,429 (258)

Nebivolol effect on doxorubicin-induced cardiotoxicity in breast cancer

, 2018
Flavia Cochera,* Daniel Dinca,* Diana Aurora Bordejevic, Ioana Mihaela Citu, Adelina Marioara Mavrea, Minodora Andor, Mihai Trofenciuc, Mirela Cleopatra Tomescu Cardiology Department, “Victor Babes” University of Medicine and Pharmacy ...
Tomescu MC, Bordejevic DA, Andor M, Cochera F, Dinca D, Citu IM, Mavrea AM, Trofenciuc M   +7 more
core  

Risk Factors Related with Doxorubicin-Induced Cardiotoxicity [PDF]

, 2018
The aim of this thesis was to evaluate risk factors related with cardiotoxicity for patients who were treated with doxorubicin. Objectives: to evaluate risk factors (age, family history of cardiovascular disease, smoking) related with doxorubicin-induced
Ambrazevičiūtė, Gretė
core  

Anthracycline Cardiotoxicity: From Bench to Bedside

, 2008
Anthracyclines remain among the most widely prescribed and effective anticancer agents. Unfortunately, life-threatening cardiotoxicity continues to compromise their usefulness.
Gianni, Luca, Herman, Eugene H, Sarvazyan, Narine, Minotti, Giorgio, Sawyer, Douglas B, Lipshultz, Steven E   +5 more
core   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

A comprehensive Sustainable Development Goal‐guided framework for advancing survivorship, rehabilitation, and quality of life in breast cancer patients

Precision Medical Sciences, EarlyView.
This article presents an Sustainable Development Goal‐aligned framework integrating survivorship care, rehabilitation, and quality‐of‐life strategies for breast cancer patients, emphasizing equity, gender responsiveness, and health system strengthening. It highlights multidisciplinary, patient‐centered interventions and global partnerships as essential
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Cardiotoxicity of Doxorubicin. A Study of Methods and Protective Interventions in Rat Models

, 2015
Introduction: The clinical use of anthracyclines, like doxorubicin, is a double-edged sword. On one side, anthracyclines play an undisputed key role in the treatment of many neoplastic diseases. On the other side; administration of anthracyclines induces
Hole, Lisa Drange
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Chemotherapy Induced Cardiotoxicity

, 2021
Cancer affects approximately 38.4% of the population and is the second leading cause of death in America. Treatment for cancer has improved and the number of cancer survivors is expected to increase from about 11.7 million in 2007 to 18 million by 2020.
Proto, Gabrielle Elizabeth, Salmon, Arlene   +1 more
core  

Radiation‐free or Chemo‐free: Rethinking the Best Strategy for PD‐L1‐High, Unresectable Stage III NSCLC

Precision Radiation Oncology, EarlyView.
This article discusses the emerging radiotherapy‐free and chemo‐free strategies in PD‐L1–high, unresectable stage III NSCLC, reviewing the Evolution trial and comparing it with existing treatments. We highlight the need for further research to validate these approaches and ensure safe de‐escalation without compromising ...
Yongbo Xiang, Nan Bi
wiley   +1 more source

Larval antibiosis to cabbage stem flea beetle (Psylliodes chrysocephala) is absent within oilseed rape (Brassica napus)

Pest Management Science, EarlyView.
We screened a panel of 98 Brassicaceae genotypes (97 Brassica napus and 1 Sinapis alba) for cabbage stem flea beetle (Psylliodes chrysocephala) larval antibiosis. We found limited evidence for antibiosis across B. napus but consistent antibiosis in S. alba. Brassicaceae relatives may therefore better inform resistance traits for breeding.
Ryan E Brock, Clara Courtney, Steven Penfield, Rachel Wells   +3 more
wiley   +1 more source