Results 101 to 110 of about 64,429 (258)

Cardiotoxicity of Cancer Chemotherapy in Clinical Practice

, 2019
Several anticancer agents are associated with significant cardiotoxicity. The list of cardiotoxic cancer therapeutic agents includes anthracyclines, trastuzumab, alkylating agents, antimetabolites, which have been in use for decades; and recently ...
Aronow, Wilbert, Jain, Diwakar
core   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Patient factors and cardiotoxicity.

, 2016
Patient factors and cardiotoxicity.
David Kotwinski (3375509), Michael Mythen (3375521), Hugh Montgomery (95769), Paul Kotwinski (3375515), Gillian Smith (462285), Jackie Cooper (448071), Julie Sanders (3375506), Dudley J. Pennell (770680), Alison Jones (377039), Louise Ma (3375512), Albert Teis (3375518)   +10 more
core   +1 more source

Food Safety Management and Mycotoxins Nexus: A Systematic Review of Mycotoxins Toxicity, Detoxification, Nutritional Impacts, and Economic Importance

Food Safety and Health, EarlyView.
The graphical abstract illustrates the interconnected relationship between food safety management, mycotoxin toxicity, and detoxification strategies, highlighting how preventive measures across the food chain can minimize mycotoxin contamination and reduce adverse health effects in humans/animals.
Chinaza Godswill Awuchi
wiley   +1 more source

Treatment factors and cardiotoxicity.

, 2016
Treatment factors and cardiotoxicity.
David Kotwinski (3375509), Michael Mythen (3375521), Hugh Montgomery (95769), Paul Kotwinski (3375515), Gillian Smith (462285), Jackie Cooper (448071), Julie Sanders (3375506), Dudley J. Pennell (770680), Alison Jones (377039), Louise Ma (3375512), Albert Teis (3375518)   +10 more
core   +1 more source

Asymptomatic Cardiotoxicity After High‐Dose Anthracycline Treatment in Sarcoma Patients Assessed by Biomarkers and Echocardiography

International Journal of Cancer, EarlyView.
ABSTRACT Treatment of sarcoma includes high‐dose anthracyclines, which can cause cardiotoxicity. This study assesses the correlation of cardiac biomarkers and echocardiographic parameters on asymptomatic cardiotoxicity in sarcoma patients treated with anthracyclines.
Elissa A. S. Polomski, Frank M. Speetjens, J. Wouter Jukema, Julius C. Heemelaar, Michiel A. J. van de Sande, Hans Gelderblom, M. Louisa Antoni   +6 more
wiley   +1 more source

Evaluation of cardiotoxicity five years after 2D planned, non-simulated, radiation therapy for left breast cancer

, 2008
Kyriaki Pistevou-Gompaki1, Apostolos Hatzitolios2, Nikos Eleftheriadis2, Evaggelos Boultoukas2, George Ntaios2, Ioannis Andronikidis2, Ioannis Tzitzikas11Department of Radiation Oncology; 2First Propedeutic Department of Internal Medicine, AHEPA Hospital,
Kyriaki Pistevou-Gompaki, et al, Nikos Eleftheriadis, Evaggelos Boultoukas, Apostolos Hatzitolios, George Ntaios   +5 more
core  

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

Deubiquitinase MYSM1 promotes doxorubicin-induced cardiotoxicity by mediating TRIM21-ferroptosis axis in cardiomyocytes

Cell Communication and Signaling
Anthracycline antitumor drug doxorubicin (DOX) induces severe cardiotoxicity. Deubiquitinating enzymes (DUBs) are crucial for protein stability and function and play a significant role in cardiac pathophysiology.
Xiaowen Shi, Jianjiang Xu, Xin Zhong, Yuanyuan Qian, Liming Lin, Zimin Fang, Bozhi Ye, Yiting Lyu, Ran Zhang, Zhanxiong Zheng, Jibo Han   +10 more
doaj   +1 more source