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Expert Opinion on Drug Safety, 2011
Anthracyclines are widely prescribed anticancer agents that cause a dose-related cardiotoxicity, often aggravated by nonanthracycline chemotherapeutics or new generation targeted drugs. Anthracycline cardiotoxicity may occur anytime in the life of cancer survivors.
Pierantonio, Menna +5 more
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Anthracyclines are widely prescribed anticancer agents that cause a dose-related cardiotoxicity, often aggravated by nonanthracycline chemotherapeutics or new generation targeted drugs. Anthracycline cardiotoxicity may occur anytime in the life of cancer survivors.
Pierantonio, Menna +5 more
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Annals of Pharmacotherapy, 1994
OBJECTIVE: To review the clinical manifestations, postulated mechanisms, and therapeutic implications of fluorouracil-induced cardiac toxicity. DATA SOURCE: A MEDLINE search was used to identify pertinent literature. STUDY SELECTION: Studies and case reports on fluorouracil cardiotoxicity were identified through a MEDLINE search.
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OBJECTIVE: To review the clinical manifestations, postulated mechanisms, and therapeutic implications of fluorouracil-induced cardiac toxicity. DATA SOURCE: A MEDLINE search was used to identify pertinent literature. STUDY SELECTION: Studies and case reports on fluorouracil cardiotoxicity were identified through a MEDLINE search.
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Doxorubicin-induced cardiotoxicity: causative factors and possible interventions.
The Journal of pharmacy and pharmacology, 2022OBJECTIVES Doxorubicin (Dox) belongs to the anthracycline drug classification and is a widely administered chemotherapeutic. However, Dox use in therapy is limited by its cardiotoxicity, representing a significant drawback of Dox treatment applicability.
I. Jones, C. Dass
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Identification of the molecular basis of doxorubicin-induced cardiotoxicity
Nature Medicine, 2012Tasneem Bawa-Khalfe, Leroy F Liu
exaly +2 more sources
Journal of Molecular and Cellular Cardiology, 1985
The morphologic-functional correlative studies that we have carried out in the past 25 years with the various catecholamines have served as an example for analyzing myocardial reaction patterns and the reactions of the cardiac muscle cells to insult.
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The morphologic-functional correlative studies that we have carried out in the past 25 years with the various catecholamines have served as an example for analyzing myocardial reaction patterns and the reactions of the cardiac muscle cells to insult.
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CARDIOTOXICITY OF AMITRIPTYLINE
The Lancet, 1972Abstract A hospital-based drug-information system has been used to extend preliminary work on the incidence of sudden unexpected death in patients with a diagnosis of cardiac disease who had been prescribed amitriptyline. The finding that there were 13 sudden unexpected deaths in a group of 119 amitriptyline patients compared with only 3 in a ...
D C, Moir +6 more
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[Anthracycline cardiotoxicity].
La Clinica terapeutica, 2003To provide specialists and general practitioners with a review of the more recent data about anthracycline-induced cardiotoxicity and diagnostic methods utilized to reveal it.Reviewers identified studies concerning anthracycline cardiotoxicity, with special emphasis to those dealing with its pathogenesis and tools utilized for diagnosing it, by ...
FINOLEZZI E +3 more
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FATAL THIORIDAZINE CARDIOTOXICITY
Medical Journal of Australia, 1979A case of fatal cardiotoxicity after a deliberate ingestion of 5000 mg thioridazine (Melleril) is reported. The serum thioridazine level is documented for the first time at the time of arrhythmia. Correct treatment of similar cases should often include insertion of a transvenous pacing wire, as the arrhythmias are generally resistant to drug therapy.
K R, Burgess +2 more
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Anthracycline-Induced Cardiotoxicity
Cardiovascular & Hematological Agents in Medicinal Chemistry, 2008The anthracyclines constitute a group of drugs widely used for the treatment of a variety of human tumors. However, the development of irreversible cardiotoxicity has limited their use. Anthracycline-induced cardiotoxicity can persist for years with no clinical symptoms.
Ferreira, Ana Lúcia dos Anjos +2 more
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Late doxorubicin cardiotoxicity
Anti-Cancer Drugs, 1992The occurrence of late congestive heart failure (CHF) as the first clinical manifestation of doxorubicin-induced cardiac toxicity is unusual in children and very rare in adults. However, subclinical cardiac dysfunction is commonly detected in children years after treatment with doxorubicin containing regimens.
M, Lishner, A, Elis, M, Ravid
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