Results 281 to 290 of about 119,936 (354)

Nanotechnology Meets Immunotherapy: Crosstalks Against Cancer

Immunity, Inflammation and Disease, Volume 14, Issue 5, May 2026.
ABSTRACT Background The convergence of nanotechnology and immunotherapy has ushered in a transformative era in cancer treatment, offering new strategies to overcome pharmacokinetic limitations and immune evasion associated with conventional therapies. While immunotherapy, spanning checkpoint inhibitors, adoptive cell transfer, and cancer vaccines, has ...
Nima Javanmehr, Asal Moazzami Ashtyani, Robabehbeygom Ghafelehbashi, Fateme Mousavi, Hossein Teimouri   +4 more
wiley   +1 more source

Integrated Omics Approach to Delineate the Mechanisms of Doxorubicin-Induced Cardiotoxicity. [PDF]

Pharmaceuticals (Basel)
Dabour MS, Abdelgawad IY, Sadaf B, Daniel MR, Grant MKO, Blaes AH, Jacobson PA, Zordoky BN.   +7 more
europepmc   +1 more source

Anti-PD-1 immune checkpoint inhibitor-induced cardiotoxicity is associated with dysfunctional metabolism, muscle wasting and autophagy. [PDF]

Sci Rep
Tichy L, Parry TL.
europepmc   +1 more source

L-Methionine attenuates methotrexate-induced cardiotoxicity by modulating oxidative stress, inflammation, and dyslipidemia in rats. [PDF]

Toxicol Rep
Abdel-Wahab WM, Daifalla NS, Essawy AE.
europepmc   +1 more source

BACH2 alleviates immune checkpoint inhibitors-induced cardiac pyroptosis via transcriptionally promoting GRSF1. [PDF]

Clin Transl Med
Cao M, Liu Z, Zhao D, Zhang H, He X, Wang W, Wang X, Yang C, Gao P, Zou Y.   +9 more
europepmc   +1 more source

Metabolomic Profiling of Tyrosine Kinase Inhibitor-Induced Endothelial Dysfunction and Cardiovascular Toxicity. [PDF]

Metabolites
Singh G, Bharaj I, Bettencourt J, Sekhon AK, Singh G, Sidhu A, Diaz EZ, Paika S, Leon A, Brar A, Brar G, Padda I, Andrade A.   +12 more
europepmc   +1 more source

Polyphenol-rich Cucurbita formulation mitigates doxorubicin-induced cardiotoxicity in rats: biochemical, histological, and molecular docking insights. [PDF]

Sci Rep
Iftikhar N, Hussain AI, Fatima T, Haji EM, Alotaibi H, Alanezi AA, Alfuraih S, Alrohily W, Alswailmi FK, Alsuwayt B, Almutairi KA, Ahmad A.   +11 more
europepmc   +1 more source

Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

Cell, 2023
Mitochondrial DNA (mtDNA) is a potent agonist of the innate immune system; however, the exact immunostimulatory features of mtDNA and the kinetics of mtDNA detection by cytosolic nucleic acid sensors remain poorly defined.
Carl W Tong, Yuanjiu Lei, Sylvia Torres-Odio   +2 more
exaly   +2 more sources

Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity

Cell Metabolism, 2023
Fasting strategies are under active clinical investigation in patients receiving chemotherapy. Prior murine studies suggest that alternate-day fasting may attenuate doxorubicin cardiotoxicity and stimulate nuclear translocation of transcription factor EB
Mualla Ozcan, Zhen Guo, Carmen Bergom
exaly   +2 more sources