Results 201 to 210 of about 3,440,112 (288)

Intersection of systemic lupus erythematosus and autoimmune thyroid disease: Shared pathophysiology, epidemiology, diagnosis, and management

Rheumatology &Autoimmunity, EarlyView.
A proposed mechanistic framework of systemic lupus erythematosus (SLE) and autoimmune thyroid disease (AITD) pathogenesis. In Stage 1, genetically susceptible individuals harbor risk variants within major histocompatibility complex (HLA) and non‐HLA loci that impair central and peripheral immune tolerance mechanisms within the thymic and peripheral ...
Elisa Elisa, Awalia Awalia, Deasy Ardiany, Henry Sutanto   +3 more
wiley   +1 more source

Cardiovascular-kidney-metabolic syndrome through the lens of gut‑derived uremic toxins. [PDF]

Gut Microbes
Xu C, Snelson M, Marques FZ.
europepmc   +1 more source

The association between red blood cell distribution width‐to‐albumin ratio and risk of insomnia: A cross‐sectional analysis of National Health and Nutrition Examination Survey and Chinese clinical data

Sleep Research, EarlyView.
Abstract Background The red blood cell distribution width‐to‐albumin ratio (RAR) is a novel composite biomarker of inflammation and nutritional status, yet its association with insomnia and underlying mechanisms remain poorly understood. Objective To investigate the association between the RAR and insomnia in two independent cohorts, comprising a ...
Jingying Ma, Jue Hu, Lei Zhang, Yilin Meng, Fa Ye, Hailun Xia, Hongmin Zhang, Yonghua Zhang   +7 more
wiley   +1 more source

Recognition and control gaps in advanced cardiovascular-kidney-metabolic syndrome among United States adults. [PDF]

Prev Med Rep
Zhou M, Zhang F, Zhou B, Lv Y.
europepmc   +1 more source

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

Small, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan, Bei Song, Chengyun Liu, Peiyu Zhong, Quan Zhou, Xiaofang Zhao, Guangyu Gao, Xinyue Zhang, Xueke Guang, Tianci Yao, Ting Liu, Hao Zhang, Xinqi Diao, Weilin Lu   +13 more
wiley   +1 more source

Atrial Cardiomyopathy in Patients with Cardiovascular-Kidney-Metabolic Syndrome: Non-Invasive Characterization (ATRIO-CKM). [PDF]

Diagnostics (Basel)
Godun MM, Marcu MT, Morariu PC, Oancea AF, Apetrii MC, Ștefan AE, Floria DE, Huiban L, Todiraș B, Pavel-Tănasă M, Trifan A, Covic A, Floria M.   +12 more
europepmc   +1 more source

Effect of Glutathione S‐Transferase and Metallothionein Polymorphisms on Mercury Levels and End‐Stage Renal Disease (ESRD) in Colombian Patients

Environmental Toxicology, EarlyView.
ABSTRACT Epidemiological studies have demonstrated a link between chronic kidney disease (CKD) and environmental mercury (Hg) exposure. Colombia has a well‐documented history of artisanal and small‐scale gold mining, where Hg exposure affects miners and nearby riverside and urban populations. This study aimed to evaluate the effects of polymorphisms in
Diana M. Narváez, Juliana Lago, Carlos Trillos, Marcela Varona, Leonardo Briceño, Ruth Marien Palma, Sonia M. Díaz, Gilma Hernández, Eliana M. Téllez, Juan Sebastián Aguilar, Daniela Castellanos, Xavier Martínez, Estefanía Zapata, Alix Rocio Barrios, Ignacio Villanueva, Michael R. Fonseca, Helena Groot   +16 more
wiley   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

Treatment of Cardiometabolic Risk Factors Among U.S. Adults With Cardiovascular-Kidney-Metabolic Syndrome. [PDF]

J Am Coll Cardiol
Gong J, Chiu N, Clinch KA, Qian Y, Ho JE, Wadhera RK.   +5 more
europepmc   +1 more source