Results 131 to 140 of about 755,361 (313)

Whole Grain Intake and Mortality From All Causes, Cardiovascular Disease, and Cancer [PDF]

, 2016
Geng Zong, Alisa Gao, Frank B. Hu, Qi Sun   +3 more
openalex   +1 more source

Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex

Advanced Science, EarlyView.
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang, Lei Dai, Zhongquan Cui, Ye Zhou, Wenyuan Dong, Hongcheng Jiang, Mengwen Wang, Xiaodan Zhong, Wei Dong, Zhang Yue, Thati Madhusudhan, Hongjie Wang, Xiong Zhong Ruan, Hesong Zeng   +13 more
wiley   +1 more source

Association of metabolic syndrome and its components with all-cause and cardiovascular mortality in the elderly

, 2017
Sang-Yhun Ju, Juneyoung Lee, Do‐Hoon Kim   +2 more
openalex   +2 more sources

Sex differences in the association between diabetes and risk of cardiovascular disease, cancer, and all-cause and cause-specific mortality: a systematic review and meta-analysis of 5,162,654 participants [PDF]

, 2019
Yafeng Wang, Adrienne O’Neil, Yurui Jiao, Lijun Wang, Jingxin Huang, Yutao Lan, Yikun Zhu, Chuanhua Yu   +7 more
openalex   +1 more source

SEVEN-YEAR SURVIVAL AND ASSOCIATIONS OF RISK FACTORS WITH ALL-CAUSE AND CARDIOVASCULAR MORTALITY AMONG RURAL RESIDENTS OF SAMARA REGION

, 2021
A. О. Myrzamatova, А. К. Kashirin, А. V. Kontsevaya, М. Л. Сиротко, D. K. Mukaneeva, M. B. Khudyakov   +5 more
openalex   +2 more sources

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Dietary patterns and all-cause, cancer, and cardiovascular disease mortality in Japanese men and women: The Japan public health center-based prospective study

, 2017
Akiko Nanri, Tetsuya Mizoue, Taichi Shimazu, Junko Ishihara, Ribeka Takachi, Mitsuhiko Noda, Hiroyasu Iso, Shizuka Sasazuki, Norie Sawada, Shoichiro Tsugane   +9 more
openalex   +2 more sources

County-Level Variation in Cardiovascular Disease Mortality in the United States in 2009–2013: Comparative Assessment of Contributing Factors [PDF]

, 2016
Shivani A. Patel, Mohammed K. Ali, K.M. Venkat Narayan, Neil K. Mehta   +3 more
openalex   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Relationships of Age at Menarche and Menopause, and Reproductive Year with Mortality from Cardiovascular Disease in Japanese Postmenopausal Women: The JACC Study

, 2006
Renzhe Cui, Hiroyasu Iso, Hideaki Toyoshima, Chigusa Date, Akio Yamamoto, Shogo Kikuchi, Takaaki Kondo, Yoshiyuki Watanabe, Akio Koizumi, Yutaka Inaba, Akiko Tamakoshi   +10 more
openalex   +2 more sources