Results 51 to 60 of about 2,147,586 (293)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Fuzzy rule-based system applied to risk estimation of cardiovascular patients [PDF]

, 2013
Cardiovascular decision support is one area of increasing research interest. On-going collaborations between clinicians and computer scientists are looking at the application of knowledge discovery in databases to the area of patient diagnosis, based on ...
Bohacik, Jan, Davis, Darryl N.
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Timely Management of Obstructive Prosthetic Valve Thrombosis

JACC: Case Reports, 2019
Obstructive bioprosthetic valve thrombosis is associated with hemodynamic compromise, and evidence on management with fibrinolysis is limited. Echocardiography is required to assess thrombus size and its effects on valve gradients, area, and leaflet ...
Elona Rrapo Kaso, MD, Steve A. Noutong, MD, LeAnn N. Denlinger, MD, Mohammed Morsy, MD, Christopher M. Kramer, MD   +4 more
doaj   +1 more source

Acute Myocardial Infarction With Cardiogenic Shock Due to Pericardial Constriction and Multivessel Coronary Obstruction

JACC: Case Reports, 2020
We present a rare case of cardiogenic shock and multivessel coronary compression due to focal pericardial inflammation and constriction. The patient was treated in the acute phase with coronary stenting and temporary mechanical support.
Matthew F. Schaikewitz, MD, Christopher B. Nnaoma, MD, Richard D. Meredith, MD, Seth Uretsky, MD, Lawrence R. Blitz, MD, Allan L. Klein, MD, Mark S. Rosenthal, MD   +6 more
doaj   +1 more source

Physician-modified aortic cuff to “stabilize” paravisceral aortic thrombus and minimize risk of distal embolization during pararenal aneurysm repair with fenestrated stent graft

Journal of Vascular Surgery Cases and Innovative Techniques, 2022
As technology and surgeon experience evolve, endovascular repair of complex abdominal aortic aneurysms is often preferred in appropriately selected patients. However, the presence of pedunculated aortic thrombus represents a relative contraindication for
Brandon Douglass, MD, Tiziano Tallarita, MD, Jason Beckermann, MD, Vinay Nijhawan, MD, Joseph Wildenberg, MD, PhD, Jeremy McBride, MD, Thomas Carmody, MD   +6 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Miniature battery-operated electromagnetic system for blood flow measurements [PDF]

, 1971
System consisting of solid state electronics package and a pair of standard flow-transducer cuffs is useful in cardiovascular studies.
Fryer, T. B.
core   +1 more source

Sleep apnea and the impact on cardiovascular risk in patients with Marfan syndrome [PDF]

, 2019
Background: Marfan syndrome (MFS) is an inherited connective tissue disorder characterized by ectopia lentis, aortic root dilation and dissection and specific skeletal features.
Bauters, Fré, De Backer, Julie, De Groote, Katya, De Wilde, Hans, De Wolf, Daniël, Dhondt, Karlien, Hertegonne, Katrien, Jordaens, Luc, Muiño Mosquera, Laura   +8 more
core   +1 more source

Hemostatic efficacy of a flowable collagen-thrombin matrix during coronary artery bypass grafting: a double-blind randomized controlled trial

Journal of Cardiothoracic Surgery, 2023
Background Flowable hemostatic agents have the advantage of being able to be applied to irregular wound surfaces and difficult to reach areas. We sought to compare the effectiveness and safety of the flowable hemostatic sealants Collastat® (collagen ...
Hyo-Hyun Kim, Kang Ju Lee, Dae Ryong Kang, Jun Hyeok Lee, Young-Nam Youn   +4 more
doaj   +1 more source