Results 101 to 110 of about 51,889 (297)
Career self-management in ascription culture [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel UniversityThe main aim of this thesis is to investigate whether theories of career self-management, developed in the USA and Western countries, apply in cultures which
Alhaddad, Masalek
core
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Sustainable Career Cards Sort (SCCS): Linking Career Choices to the World Needs [PDF]
Recently, there has been a call for career counseling interventions that promote the construction of a more humane sustainable world. In fact, contemporary world is facing collateral crises at various levels, and career counselors should be able to help ...
Shékina Rochat +3 more
core +1 more source
The matrix of linguistic exclusions impeding career construction for D/deaf learners. [PDF]
Stemela-Zali U, Kathard H, Sefotho MM.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
We actualize the process of formation of career strategies for students in conditions of self-management. Student self-management is considered from the standpoint of social and cultural activity and is defined as a special form of initiative ...
V. K. Botkova, E. I. Grigorieva
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Developing Career Capital for Global Careers: The Role of International Assignments [PDF]
Creating organizational processes which nurture global careers is a key task for global companies. International assignments are normally viewed as positive by both individuals and organizations for the development of global career competencies.
Dickmann, Michael, Harris, Hilary
core
A Thematic Analysis of Career Adaptability in Retirees Who Return to Work
Retirement can no longer be conceptualized as disengagement, as the end of a person’s career, as it is in the life-span, life-space theory. Increasingly, retirees are returning to work, in paid and unpaid positions, in a part-time or full-time capacity,
Jennifer eLuke +2 more
doaj +1 more source

