Results 91 to 100 of about 51,889 (297)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
What can disabled academics' career experiences offer to studies of organization? [PDF]
, 2011 Whilst there have been calls to theorize and explore how disability and ableism are constructed through organizing processes as a contribution to the critique of knowledge construction in organization studies (Harlan and Robert, 1998; Hearn and Parkin ...
Williams, Jannine
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Building career capital: Helping workers to enhance career mobility in uncertain times [PDF]
, 2019 There is evidence that organisational career role holders are changing roles more frequently. Despite this, career theories such as the career capital lens have so far neglected this role transition context.
Brown, Cathy, Wond, Tracey
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Importance of family support in planning educational and professional careers by young adults from Generation Z [PDF]
Studia z Teorii WychowaniaThe construction of educational and professional careers is the subject of research in many scientific studies. The research carried out is based on very diverse scientific concepts.
Katarzyna Jagielska
doaj +1 more source
Constructing Your Career Plays
Sports Innovation Journal, 2022 The evolving landscape of job opportunities has led to increased concerns around life-career success of college student-athletes while and after they balance their academic and sport performance. At Kent State University (Division I) located in Kent, Ohio, Tracy Montgomery serves as the student-athlete career advisor liaison between Career Exploration &
openaire +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Men in non-traditional occupations: Career entry, career orientation and experience of role strain [PDF]
, 2006 This paper sets out to explore the experiences of men in non-traditional occupations. In particular it focuses on the dynamics of career entry, career orientation (i.e. preference for intrinsic or extrinsic rewards) and the possible existence, nature and
Simpson, R
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International Journal for Research in Vocational Education and TrainingBackground: The Career Construction Theory (CCT) focuses on the active role people can play when they create and design their singular paths for career success.
Enrique Merino-Tejedor +3 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
The impact of training and development towards women's career in construction: research methodological perspective [PDF]
The UK construction industry has a particularly low participation rate of women, both for those employed in the industry and for those engaged in training.
Amaratunga, Dilanthi +2 more
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