Results 71 to 80 of about 925,551 (292)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Mentoring Entrepreneurial Networks : mapping conceptions of participants in technological-based business incubators in Brazil [PDF]

open access: yes, 2007
La agenda de la investigación reciente sobre emprendedores incluye el análisis de las estructuras cognitivas de los empresarios de éxito, revelándose como una herramienta importante a la hora de examinar una trayectoria emprendedora. Mediante técnicas de
Bittencourt Bastos, Antonio Virgilio   +3 more
core   +4 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Online career construction for a trauma survivor with career choice ambivalence

open access: yesSouth African Journal of Higher Education
This article reports on the online administration of career construction counselling for a trauma survivor who sought help in resolving her career-choice ambivalence (uncertainty). The participant was purposively selected from a group of people attending
J. G. Maree
doaj   +1 more source

Occupation Profile: Librarians, October 5, 2017 [PDF]

open access: yes, 2017
Construct, erect, install or repair structures and fixtures made of wood, such as concrete forms; building frameworks, including partitions, joists, studding, and rafters; and wood stairways, window and door frames, and hardwood floors.

core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Career advancement of the professional women in the UK construction industry: Career success factors [PDF]

open access: yes
The issue regarding the lack of women in the UK construction industry has become more prominent for some time, attracting government and industry wide attention due to this potential skill shortage facing the industry.
Amaratunga, Dilanthi   +2 more
core  

Bottom-Up Organizing in the Trades: An Interview with Mike Lucas, IBEW Director of Organizing [PDF]

open access: yes, 1988
[Excerpt] Like the bottom-up organizers who built the IBEW 100 years ago by traveling from city to city, working at their trade and preaching the union creed, Lucas has been around the block. From Florida to Oklahoma, Indiana to Tennessee, he worked from
Grabelsky, Jeff
core   +1 more source

Career construction as a way of resolving career indecision

open access: yesSouth African Journal of Higher Education, 2016
This article reports on the value of career construction counselling for a woman who was undecided about the career she should follow. The participant was purposefully selected from a number of people taking part in a career construction counselling course.
openaire   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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