Results 61 to 70 of about 3,763,257 (287)

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Career adaptability as an instructional scaffold for career education in South African schools

African Journal of Career Development
Background: South African learners need more career preparation, as it provides a sense of control in the current economic climate of high unemployment, as confirmed by the business sector.
Marlene Algra, Hermien Olivier
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Prompting reflection and learning in career construction counseling [PDF]

, 2016
Adopting the overall framework provided for an international inquiry into career counseling interventions, this article reports on a qualitative study into the efficacy of a relatively new approach to practice in England.
Reid, H., Reid, Hazel, Brown, Alan, Brown, A., Bimrose, Jenny, Bimrose, J.   +5 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Career construction as a way of resolving career indecision

South African Journal of Higher Education, 2016
This article reports on the value of career construction counselling for a woman who was undecided about the career she should follow. The participant was purposefully selected from a number of people taking part in a career construction counselling course.
openaire   +3 more sources

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Russian Version of the Career Crafting Assessment (CCA): Psychometric Testing and Validation

Psychology in Russia: State of Art
Background. Rapid changes in work and career systems have increased the importance of proactive career regulation. Career crafting refers to intentional behaviors through which individuals shape career-related resources, relationships, meanings, and task
Anastasia S. Yakukhnova, Larisa V. Mararitsa, Svetlana D. Gurieva   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Mark Savickas’ theory as an inspiration for professional counselling aimed at adults enhanced with the application of Diagnostic and Simulation Games Method

Rocznik Andragogiczny, 2016
In case of adult learners, the process of professional counselling, diagnosing of professional predispositions or providing support for learners in their professional career construction frequently requires the application of different methods and ...
Przemysław Ziółkowski
doaj   +1 more source