Results 101 to 110 of about 15,240,876 (259)

Development Effectiveness Overview (DEO) 2020

open access: yes, 2020
The Development Effectiveness Overview (DEO) is an annual report produced by the IDB Group to share the results and impact of its work in Latin America and the Caribbean.
Inter-American Development Bank
core   +1 more source

Educational Impact of Generalist–Specialist Collaborative Outpatient Training for Medical Students: A Qualitative Study

open access: yesJournal of General and Family Medicine
Background Despite the recognized benefits of specialty outpatient training for medical students, such settings present educational challenges. To address these, our university incorporated generalist support into specialty outpatient education.
Koki Nakamura   +4 more
doaj   +1 more source

A Digital Twin Architecture for Forest Restoration: Integrating AI, IoT, and Blockchain for Smart Ecosystem Management

open access: yesFuture Internet
Meeting global forest restoration targets by 2030 requires a transition from labor-intensive and opaque practices to scalable, intelligent, and verifiable systems.
Nophea Sasaki, Issei Abe
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

How the internet changed career: framing the relationship between career development and online technologies [PDF]

open access: yes, 2012
This article examines the inter-relationship\ud between the internet and career development. It asks\ud three inter-linked questions: How does the internet\ud reshape the context within which individuals pursue\ud their career?
Hooley, Tristram
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Parent and Adolescent Perceptions of Adolescent Career Development Tasks and Vocational Identity

open access: yes, 2018
We surveyed Australian adolescents and parents to test differences and congruence in perceptions of adolescent career development tasks (career planning, exploration, certainty, and world-of-work knowledge) and vocational identity.
Praskova, Anna   +2 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Application of Immersive Virtual Reality in the Training of Future Teachers: Scope and Challenges

open access: yesVirtual Worlds
Introduction: The integration of Immersive Virtual Reality (IVR) into teacher education is a significant innovation that can enhance the learning and practical training of future teachers.
Carlos Arriagada-Hernández   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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