Results 61 to 70 of about 705,010 (250)

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Individual Ambidexterity as a Driver of Career Sustainability in Late Careers

Encyclopedia
Individual ambidexterity is the capacity of an individual to engage in both exploration of new knowledge, roles, and opportunities and exploitation of existing skills, experience, and routines in ways that support adaptation and sustained work ...
Teresa Dieguez
doaj   +1 more source

Career inhibitors and career enablers for executive women [PDF]

This paper is intended to contribute to the study of career inhibitors and career enablers for women. The analysis is based on data obtained from a survey conducted by the International Center of Work and Family at IESE Business School.
Leon, Consuelo, Torres, Elizabeth, Chinchilla, Nuria, Canela, Miguel A.   +3 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Career Insider April 2010

, 2010
Issue of Career Insider, a publication of the University of Scranton's Office of Career ...
University of Scranton. Office of Career Services
core   +1 more source

Career Insider December 2013

, 2013
Issue of Career Insider, a publication of the University of Scranton's Office of Career ...
University of Scranton. Office of Career Services
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

“Luck of the draw really”: a qualitative exploration of Australian trainee doctors’ experiences of mandatory research

BMC Medical Education
Background Many medical trainees, prior to achieving specialist status, are required to complete a mandatory research project, the usefulness of which has been debated.
Caitlin Brandenburg, Joanne Hilder, Christy Noble, Rhea Liang, Kirsty Forrest, Hitesh Joshi, Gerben Keijzers, Sharon Mickan, David Pearson, Ian A. Scott, Emma Veysey, Paulina Stehlik   +11 more
doaj   +1 more source

Perceptions, barriers, and aspirations: understanding Grade 9 girls’ interest in STEM through three-day enrichment programs

Frontiers in Education
The underrepresentation of women in university science programs highlights the need to understand factors influencing schoolgirls’ Science, Technology, Engineering, and Mathematics (STEM) career choices. We applied the socio-cognitive career theory (SCCT)
Rahul Choudhary, Maria Parappilly, Richard Woodman   +2 more
doaj   +1 more source