Results 51 to 60 of about 1,993,068 (279)

Career development learning in higher education: how authentic work experiences and opportunities for career exploration canincrease self-efficacy and inform career identity [PDF]

open access: yes, 2015
A recent study suggests that enhancing career development is a key motivator for students entering university (Kandiko & Mawer, 2013). This article discusses the place of career development learning within the ‘employability’ agenda.
Benton, Paula
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Process of career identity formation among adolescents: components and factors

open access: yesHeliyon, 2020
To qualitatively explore the process and factors that influence career identity formation, data were collected from 18 middle adolescents of age ranged between 15 and 17 years.
Syeda Shahida Batool, Saba Ghayas
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

UNO Website ACDC Academic and Career Development Center [PDF]

open access: yes, 2016
We facilitate academic and career success and career development with resources and services for academic and career ...
Academic and Career Development Center, UNO
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Individual characteristics and career exploration in adolescence [PDF]

open access: yes, 1998
The effects of gender, age and school grade on several career exploration dimensions measured by the Career Exploration Survey were investigated. Subjects were high school students facing an imminent career decision.
Silva, M. Carolina   +3 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Career-related psychological cognitions and career exploration behavior among Chinese college students: statistical indirect pathways through generative artificial intelligence use

open access: yesFrontiers in Psychology
Generative artificial intelligence is changing how college students access career information, understand career opportunities, and prepare for job searching.
Qiang Lü   +4 more
doaj   +1 more source

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