Results 41 to 50 of about 6,123,875 (286)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Hope as a resource for career exploration: Examining incremental and cross-lagged effects [PDF]

, 2015
Hope is believed to be beneficial for vocational pursuits, but the question of how and why hope is related to pivotal career development variables remains largely unaddressed.
Abessolo, Marc, Abessolo, M., Froidevaux, A., Hirschi, A., Hirschi, Andreas, Froidevaux, Ariane   +5 more
core   +1 more source

Career Exploration Data Repository

, 2022
Personality Predictors of Career Exploration: A Meta-Analysis Supplementary ...
Samuel D Lee
core   +3 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Perceived social support as predictors of adolescents’ career exploration

, 2014
The aim of this study was to examine whether adolescents’ career exploration is predicted by perceived social support. Participants were 718 seventh, eighth, ninth and tenth grade students.
Çelik, E., Turan, M. E., Turan, E., Mehmet Emin Turan, Turan, Erkan, Erkan Turan, Eyüp Çeli̇k   +6 more
core   +1 more source

Individual Ambidexterity as a Driver of Career Sustainability in Late Careers

Encyclopedia
Individual ambidexterity is the capacity of an individual to engage in both exploration of new knowledge, roles, and opportunities and exploitation of existing skills, experience, and routines in ways that support adaptation and sustained work ...
Teresa Dieguez
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Adjustment to university among university students: a correlational study

Interação em Psicologia, 2007
The purpose of this study was to investigate possible correlates of adjustment to University among University students. Five dimensions of adaptation (career, personal, interpersonal, study, and institutional) were correlated with the following variables:
Marco Antonio Pereira Teixeira, Graciele Dotto Castro, Luciane da Rosa Piccolo   +2 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The association between socioeconomic status and career preparation of Sino-Kazakh college students: multiple psychological mechanisms of perceived university support and career adaptability

Frontiers in Psychology
IntroductionAmidst the evolving global labor market, college students’ career preparation demonstrates a close link with family backgrounds and higher education contexts. Grounded in the integrated framework of Career Construction Theory (CCT) and Social
Xiaogang Jin, Xiaogang Jin, Aigul Alchimbayeva, Junxian Li, Xintian Lyu, Zhan Zhou, Chunling Wang   +6 more
doaj   +1 more source