Results 51 to 60 of about 6,123,875 (286)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Protean and Boundaryless Career Attitudes in New Zealand Workers [PDF]

open access: yes, 2010
This study explored protean and boundaryless career attitudes in a sample of New Zealand workers. Recent changes to both organisational and societal structures have significantly altered how careers are acted out.
Morrell, Heather Rebecca
core  

Escalas de exploração vocacional (EEV) para universitários Escalas de exploración vocacional (EEV) para universitarios Vocational exploration scales (VES) for university students

open access: yesPsicologia em Estudo, 2007
O comportamento exploratório tem sido descrito na literatura como um aspecto fundamental do desenvolvimento de uma carreira ao longo do ciclo vital.
Marco Antônio Pereira Teixeira   +2 more
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Business ethics: Challenge for management [PDF]

open access: yesAnali Ekonomskog fakulteta u Subotici, 2015
In this paper authors try to represent and analyze research results, which indicate changes in business behavior ethics with respect to possible business situation under consideration among students.
Vranešević Tihomir
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Career Development of College Students through Part-Time Work: The Role of Leader-Member Exchange and Taking Charge Behavior [PDF]

open access: yes
This study examines the potential benefit of college students' part-time work on their career development by focusing on leader-member exchange (LMX) and taking charge behavior in the workplace.
Tomoki Sekiguchi
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Influence of career self-efficacy beliefes on career exploration behavior [PDF]

open access: yes, 2007
Thesis (M.S.)--State University of New York at New Paltz, 2007, Psychology DepartmentThe study involved 211 female and 47 male (259 total) college students from the State University of New York at New Paltz general population.
Nasta, Kristen A.
core  

Developing a curriculum framework for vocational competency in college students with disabilities: based on RCF and ICF

open access: yesZhongguo kangfu lilun yu shijian
Objective To develop a professional competency-oriented higher education curriculum system for college students with disabilities based on rehabilitation competency framework (RCF) and International Classification of Functioning, Disability and Health ...
GUAN Shan   +5 more
doaj   +1 more source

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