Results 71 to 80 of about 370,343 (289)

Learning Methods for Supporting Professional Development of Young People: the Contribution of Teachers and Parents

open access: yesAstra Salvensis, 2019
Children and adolescents develop optimally when their most important socialization contexts work together constructively. This study examines the extent to which in the area of vocational guidance, in addition to the support provided individually by ...
Nurbol SAYATBEKOV, Aibek GABDULLIN
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The career experiences of industrial and organisational psychology graduates [PDF]

open access: yes, 2013
A survey of 53 graduates of industrial and organizational psychology masters programs, from the four universities in New Zealand offering such programs (Auckland, Canterbury, Massey, Waikato), was conducted to explore their early career experiences.
Cable, Donald Alfred James
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Editorial

open access: yesScience Education International
In this June 2024 issue of the Science Education International, we are proud to present an array of scholarly articles that highlight the diverse and innovative approaches to science education from ten different countries: Türkiye, Greece, Estonia ...
Bulent Cavas
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

The Political Cost of Corruption: Scandals, Campaign Finance, and Reelection in the Brazilian Chamber of Deputies

open access: yesJournal of Politics in Latin America, 2016
While corruption is widely disapproved of, some corrupt politicians continue to win elections. We tackle this paradox by examining the effects of malfeasance scandals in politicians’ behavior.
Ivan Chaves Jucá   +2 more
doaj  

Enhancing choice? The role of technology in the career support market [PDF]

open access: yes, 2010
This report explores the role that technology has played in the development of the career support market. This market is conceived broadly to include all possible resources that individuals might draw upon to support them in their career development.
Hooley, Tristram   +2 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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