Results 121 to 130 of about 670,324 (285)

The role of skills from worklessness to sustainable employment with progression [PDF]

open access: yes, 2011
This study is shaped by the recognition that while there has been a great deal of policy development around the transition from unemployment and inactivity to employment over the last decade, policy has not been sufficiently informed about how best to ...
Bickerstaffe, Tim   +6 more
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Operating and Managing Street Outreach Services [PDF]

open access: yes, 2011
Increasingly, cities have added street outreach to the mix of strategies used in comprehensive gang reduction efforts, drawing upon mounting evidence of impact.
Angela M. Wolf, Livier Gutierrez
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

How Career Interventions and Digital Career Counselling Affect Students’ Career Maturity

open access: yesAdvances in Social Science, Education and Humanities Research, 2022
Dadang Lukman Hakim, null Arismen
openaire   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

\u27Turning Hearts to Break Off the Yoke of Oppression\u27: The Travels and Sufferings of Christopher Meidel, c. 1659-c. 1715

open access: yes, 2015
This study of Christopher Meidel, a Norwegian Quaker writer imprisoned both in England and on the Continent for his beliefs and actions, explores the life of a convert to Quakerism and his missionary zeal in the early eighteenth century. From Meidel\u27s
Allen, Richard
core  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Evidence-Based Interventions that Promote Resident Wellness from the Council of Emergency Residency Directors [PDF]

open access: yes, 2020
Initiatives for addressing resident wellness are a recent requirement of the Accreditation Council for Graduate Medical Education in response to high rates of resident burnout nationally.
Bailitz, John   +6 more
core  

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