Results 41 to 50 of about 90,086 (258)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Stroke survivors’ health literacy is not associated with caregiver burden: a cross-sectional study

Scientific Reports
Caregivers to stroke survivors often experience a multifaceted strain defined as caregiver burden. Low health literacy among caregivers may contribute to increased caregiver burden but there is limited research specifically examining the association ...
Andrea Hess Engström, Sebastian Lindblom, Maria Flink, Susanna Söderberg, Lena von Koch, Charlotte Ytterberg   +5 more
doaj   +1 more source

153 Caregiving burden and resilience: a mixed methods analysis in dyads managing a VAD in the home

Journal of Clinical and Translational Science, 2022
OBJECTIVES/GOALS: Caregivers of patients with ventricular assist devices (VAD) are invaluable contributors to patient health, but they may experience psychological symptoms or worsening quality of life related to caregiving.
Anna Peeler, Martha Abshire Saylor, Lauren Choy, Lyndsay DeGroot, Noelle Pavlovic, Patricia Davidson, Julie T. Bidwell   +6 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Caregiver's burden in rehabilitation of patients with neurological deficits following traumatic spinal cord injury

Journal of Spinal Surgery, 2017
Introduction: Traumatic spinal cord injury (SCI) is an emerging public health problem reaching epidemic proportions. Reduced functional capacity after SCI not only affects the quality of life (QOL) of the patient, but also creates an added social ...
Vinu V Gopal, P T Baburaj, P K Balakrishnan   +2 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Does family confidence bridge child functioning and caregiver burden in early intervention?

PLoS ONE
BackgroundEnhancing caregivers' confidence and competence in early childhood intervention is a priority, focusing on collaboration between professionals and families to improve family well-being and quality of life.
Gabriel Martínez-Rico, Pau García-Grau, Margarita Cañadas-Pérez, Rómulo J González-García   +3 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Burden faced by caregivers of stroke patients who attend rural-based medical teaching hospital in western India

Annals of Indian Academy of Neurology, 2020
Background: Stroke results in significant caregiver burden and strain. Objective: The main objectives of this study is to assess the burden and its consequences in caregivers of stroke patients and to determine the associated factors to caregivers ...
Bhavin Mandowara, Alpa N Patel, Amee A Amin, Ajay Phatak, Soaham Desai   +4 more
doaj   +1 more source

Heart Failure Caregiver Burden and Outcomes: A Systematic Review

Journal of Primary Care & Community Health, 2022
Introduction/Objective: This review aimed to summarize articles describing caregiver burden and the relationship between health outcomes as well as describing interventions focusing on this population.
Wanich Suksatan, Thitipong Tankumpuan, Patricia M. Davidson   +2 more
doaj   +1 more source