Results 21 to 30 of about 67,090 (139)
Carnitine (β-hydroxy-γ-trimethyl amino butyrate) is, a vitamin-like substance carrying long-chain fatty acids into the mitochondrial matrix. Due to its effect in energy metabolism, carnitine plays an important role in controlling diabetes and its ...
Özer Şehriban Duyar +1 more
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Secondary Carnitine Deficiency in Dialysis Patients: Shall We Supplement It? [PDF]
Carnitine, essential for fatty acid β-oxidation, is obtained from diet and through de novo biosynthesis. The organic cation/carnitine transporter 2 (OCTN2) facilitates carnitine cellular transport and kidney resorption.
Ronald J.A. Wanders +3 more
doaj
Plasma Targeted Metabolomics Analysis for Amino Acids and Acylcarnitines in Patients with Prediabetes, Type 2 Diabetes Mellitus, and Diabetic Vascular Complications [PDF]
Background We hypothesized that specific amino acids or acylcarnitines would have benefits for the differential diagnosis of diabetes. Thus, a targeted metabolomics for amino acids and acylcarnitines in patients with diabetes and its complications was ...
Xin Li +5 more
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Circulating Carnitine Levels and Breast Cancer: A Matched Retrospective Case-Control Study
IntroductionEpidemiological studies investigating the association between carnitine and breast cancer are scarce.Materials and MethodsThis 1:1 age-matched retrospective case-control study identified 991 female breast cancer cases and 991 female controls ...
Jiayi Zhang +9 more
doaj +1 more source
Background: Carnitine supplementation improves various dialysis-related symptoms including erythropoietin-resistant anemia in patients who are undergoing hemodialysis.
Shohei Kaneko +6 more
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Potential TMA-Producing Bacteria Are Ubiquitously Found in Mammalia
Human gut bacteria metabolize dietary components such as choline and carnitine to trimethylamine (TMA) that is subsequently oxidized to trimethylamine-N-oxide (TMAO) by hepatic enzymes.
Silke Rath +4 more
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ObjectivesMild cognitive impairment (MCI), an early stage of cognitive decline preceding dementia, poses a growing public health concern, especially in aging populations.
Ling Yuan +9 more
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Background: This study was performed to evaluate the effects of carnitine administration on carotid intima-media thickness (CIMT) and inflammatory markers in women with polycystic ovary syndrome (PCOS).
Hamid Reza Talari +7 more
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L-Carnitine (L-CAR) and acetyl-L-carnitine (Acetyl L-CAR) are the essential cofactor compounds in lipid metabolism and are used in the treatment of various diseases.
Cemil Aydoğan +2 more
doaj +1 more source
Neonatal carnitine concentrations in relation to gestational age and weight
Background Free carnitine has been measured in the Dutch newborn screening (NBS) program since 2007 with a referral threshold of ≤5 μmol/L, regardless of gestational age or birthweight.
Loek L. Crefcoeur +10 more
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