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Carnosine supplementation improves cognitive outcomes in younger participants of the NEAT trial. [PDF]
O'Toole TE +6 more
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Bacterial Adaptation to Stress Induced by Glyoxal/Methylglyoxal and Advanced Glycation End Products. [PDF]
Kuczyńska-Wiśnik D +2 more
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Serum Concentrations of Imidazole Dipeptides and Serum Amyloid A in a Bottlenose Dolphin (<i>Tursiops truncatus</i>) with Rhabdomyolysis: Potential Biomarkers for Muscular Damage. [PDF]
Arakawa N +7 more
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Physiology and Pathophysiology of Carnosine
Physiological Reviews, 2013Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal muscle, but also in other excitable tissues. Most animals, except humans, also possess a methylated variant of carnosine, either anserine or ophidine/balenine, collectively called the ...
Giancarlo Aldini, Wim Derave
exaly +3 more sources
Carnosine and Carnosine-Related Antioxidants: A Review
Current Medicinal Chemistry, 2005First isolated and characterized in 1900 by Gulewitsch, carnosine ( β-alanyl-L-hystidine) is a dipeptide commonly present in mammalian tissue, and in particular in skeletal muscle cells; it is responsible for a variety of activities related to the detoxification of the body from free radical species and the by-products of membrane lipids ...
Andrea Guiotto +3 more
openaire +4 more sources
Carnosine and Diabetic Nephropathy
Current Medicinal Chemistry, 2020Diabetic Nephropathy (DN) is a major complication in patients with type 1 or type 2 diabetes and represents the leading cause of end-stage renal disease. Novel therapeutic approaches are warranted. In view of a polymorphism in the carnosinase 1 gene CNDP1, resulting in reduced carnosine degradation activity and a significant DN risk reduction ...
Verena, Peters +2 more
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Current Medicinal Chemistry, 2020
Carnosine (β-alanyl-L-histidine) is a small dipeptide with numerous activities, including antioxidant effects, metal ion chelation, proton buffering capacity, and inhibitory effects on protein carbonylation and glycation. Carnosine has been mostly studied in organs where it is abundant, including skeletal muscle, cerebral cortex, kidney, spleen, and ...
Ken-Ichiro, Tanaka, Masahiro, Kawahara
openaire +2 more sources
Carnosine (β-alanyl-L-histidine) is a small dipeptide with numerous activities, including antioxidant effects, metal ion chelation, proton buffering capacity, and inhibitory effects on protein carbonylation and glycation. Carnosine has been mostly studied in organs where it is abundant, including skeletal muscle, cerebral cortex, kidney, spleen, and ...
Ken-Ichiro, Tanaka, Masahiro, Kawahara
openaire +2 more sources
Carnosine in Nucleated Erythrocytes
Nature, 1974IN the course of studies of the metabolism of intracerebrally administered L-U-14C-histidine in brains of mice and frogs (Rana pipiens), analyses were also performed on blood samples from the injected animals. The mice received 1.5×106 c.p.m. of the labelled histidine, and 1 h later samples of blood were taken by means of orbital puncture.
J N, Van Balgooy +2 more
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