Results 51 to 60 of about 42,710 (335)

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo   +9 more
wiley   +1 more source

Adapting a Markov Monte Carlo simulation model for forecasting the number of Coronary Artery Revascularisation Procedures in an era of rapidly changing technology and policy

open access: yesBMC Medical Informatics and Decision Making, 2008
Background Treatments for coronary heart disease (CHD) have evolved rapidly over the last 15 years with considerable change in the number and effectiveness of both medical and surgical treatments.
Knuiman Matthew   +2 more
doaj   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated With Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

open access: yesArthritis &Rheumatology, EarlyView.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA) and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serologic markers. Methods We analyzed serum and plasma from three cohorts: presymptomatic individuals who later developed RA ...
Outi Sareila   +12 more
wiley   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou   +10 more
wiley   +1 more source

Anti–Carbamylated Fibrinogen Autoantibodies of IgG and IgA Isotypes Contribute to a Better Prognostic Stratification in Very Early Rheumatoid Arthritis: Data From the French National ESPOIR Cohort

open access: yesArthritis &Rheumatology, EarlyView.
Objective The aim of this study was to investigate the prevalence and longitudinal evolution of anti–carbamylated fibrinogen antibodies (ACa‐Fib) of IgG and IgA isotypes in early rheumatoid arthritis (RA) and determine whether these antibodies provide additional diagnostic and prognostic information beyond anti–cyclic citrullinated peptide (anti‐CCP ...
Pauline Brevet   +11 more
wiley   +1 more source

Comparison of rearing performances and intermuscular bone number in the mirror and nude genotypes of common carp (Cyprinus carpio L.) in a controlled field test in Madagascar

open access: yesAquaculture Reports, 2016
Nude carps, a genotype of common carp which are devoid of scales, have been banned from farmed populations of carp in Europe due to both the lethal effect of the N (nude) gene when in homozygous state, and to the negative pleiotropic effects on growth ...
Diana Edithe Andria-Mananjara   +2 more
doaj   +1 more source

Carps breeding technology in the fish breeding-ground of Laukysta [PDF]

open access: yes, 2010
The aim of experiment - carps breeding technology in the fishes breeding – ground of Laukysta. The tasks of experiment: 1. Fishery in Lithuanian; 2. Lithuanian state of aquaculture; 3. The fishes breeding - ground and work specifics of Laukysta. 4.
Salinkaitė, Gintarė
core  

Climate Action Response Plans in Firms: Exploring the Characteristics of Firms Planning for a More Sustainable Future

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Firm‐level Climate Action Response Plans (CARPs) comprise firms' climate change mitigation and adaptation commitments. Encouraging firms to develop CARPs is thus vital for meeting ever‐pressing climate goals. Understanding the resources and capabilities facilitating firms to develop CARPs can inform evidence‐based approaches to accelerate ...
Helena Lenihan   +2 more
wiley   +1 more source

Impact of Lactic Acid on Formation of Biogenic Amines in Common Carp

open access: yesMedical Laboratory Journal, 2016
Background and Objective: Raw fish is a highly perishable product that deteriorates due to chemical changes and microbial growth. Biogenic amines (BAs) are generated in course of bacterial spoilage in fish that may lead to BA toxicity, particularly in ...
Seyyed Mohammad Ali Noori   +4 more
doaj  

Physiological parameters of Amur carps Cyprinus rubrofuscus (Lacépède 1803) under anesthesia following painful stimulus

open access: yesAquaTechnica
The aim of this trial was to evaluate heart rate, opercular frequency, blood parameters and cortisol levels in Amur carps (Cyprinus rubrofuscus) anesthetized in benzocaine-based solutions at concentrations of 70, 100 and 130 mg/L (B70, B100 and B130) or
André Luiz Veiga Conrado andreconrado   +5 more
doaj   +1 more source

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