Emerging experience with meningococcal serogroup B protein vaccines
Introduction: The successful development of two broadly protective vaccines targeting Neisseria meningitidis serogroup B (MenB); 4CMenB and rLP2086, is the most significant recent advance in meningococcal disease prevention. Areas covered: Here we review
Daniela Toneatto +3 more
doaj +1 more source
Preventive measures in infancy to reduce under-five mortality: a case-control study in The Gambia.
OBJECTIVE: To investigate the relationship between child mortality and common preventive interventions: vaccination, trained birthing attendants, tetanus toxoid during pregnancy, breastfeeding and vitamin A supplementation. METHODS: Case-control study in
Adegbola, Richard A +8 more
core +1 more source
Intestinal carriage of Staphylococcus aureus: How does its frequency compare with that of nasal carriage and what is its clinical impact? [PDF]
The bacterial species Staphylococcus aureus, including its methicillin-resistant variant (MRSA), finds its primary ecological niche in the human nose, but is also able to colonize the intestines and the perineal region.
A Bhalla +102 more
core +3 more sources
2459. Prevalence of Nasopharyngeal Carriage of Macrolide and Lincosamide Resistance Genes Among a Household-based cohort of Children and Adults in a Peri-urban Community in Peru [PDF]
Cara Charnogusrky +10 more
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Prophylaxis of asymmetric carriage of schoolboys of middle age by facilities of physical rehabilitation. [PDF]
The questions of violation of carriage are considered in a frontal plane for schoolboys of middle age. In research took part 20 schoolboys (girls and boys) of 12-14 years old. The estimation of the state of carriage is executed.
Gulbani R.Sh. +2 more
doaj
Concentric differential gearing arrangement [PDF]
Two input members and two concentric rotatable output members are interconnected by a planetary gear arrangement. The first input drives directly the first output. The second input engages a carrier having the planetary gears affixed thereto. Rotation of
Gerdts, J. C., Zeiger, R. J.
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

