Results 111 to 120 of about 168,461,955 (277)
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Iz teksta: ''(...) Konačan tekst Jedinstvenih pravila usvojen je na Generalnoj skupštini CMI-ja, održanoj 29.6.1990. u Parizu, nakon dužeg vremena pronalaženja odgovarajućih kompromisnih rješenja.
Dorotea Ćorić
doaj
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Entropy as an Objective Function of Optimization Multimodal Transportations. [PDF]
Bazaluk O, Kotenko S, Nitsenko V.
europepmc +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Carriage of goods by sea - from Hague to Rotterdam : safer waters
The back bone of international trade has always been international transport. Without good transport networks, the movement of goods and services from one frontier to another would be an uphill task, and would greatly hinder development in international ...
Metuge Denning N
core
Identitet prijevoznika kod time-chartera : [prikaz presude i komentar]
Za utvrđivanje identiteta prijevoznika kod time charter-a bitan je sadržaj teretnice, a ne pravna priroda time chartera. Činjenice da je teretnica potpisana ''za zapovjednika'' i da je u teretnici sadržana klauzula o identitetu prijevoznika ...
Časlav Pejović
doaj
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source

