Results 101 to 110 of about 2,646,292 (297)

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

A high-frequency silicon-graphene-germanium barristor

Nature Communications
Realising ubiquitous environmental monitoring and smart sensing devices compatible with Internet of Things (IoT) and 6 G networks requires transistors with terahertz (THz) cutoff frequencies (f T) for efficient signal processing.
Xiaoyue Wang, Shaotang Sun, Zishen Qiao, Haiyan Jiang, Changze Li, Haitao Jiang, Jing Bai, Xubo Song, Xufan Li, Xinzhe Wang, Xi Zhu, Shun Feng, Bo Li, Jinhua Liang, Lingfei Wang, Zhongying Xue, Yutaka Ohno, Jianjun Gao, Zengfeng Di, Dongming Sun, Chi Liu   +20 more
doaj   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Financing obstacles among euro area firms: Who suffers the most? [PDF]

In this study we investigate the determinants of financing obstacles using survey data on a sample of around 5000 firms from the euro area countries. This completely new survey – started at the end of 2009 - gives us the opportunity to test whether firm ...
Griesshaber, Nicolas, Ferrando, Annalisa
core  

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Multiple-Carrier-Lifetime Model for Carrier Dynamics in InGaN/GaN LEDs with Non-Uniform Carrier Distribution (Supplementary Material)

Multiple-Carrier-Lifetime Model for Carrier Dynamics in InGaN/GaN LEDs with Non-Uniform Carrier Distribution (Supplementary Material)
Xuefeng Li, Elizabeth DeJong, Rob Armitage, and Daniel Feezell (17668002)
core   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Import of ADP/ATP carrier into mitochondria [PDF]

, 1990
We have identified the yeast homologue of Neurospora crassa MOM72, the mitochondrial import receptor for the ADP/ATP carrier (AAC), by functional studies and by cDNA sequencing.
Dietmeier, Klaus A., Söllner, Thomas, Pfaller, Rupert, Tropschug, Maximilian, Pfanner, Nikolaus, Steger, Heinrich F., Kiebler, Michael, Neupert, Walter, Trülzsch, Konrad S.   +8 more
core   +1 more source

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

Advanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu, Hsi‐wen Wu, Xiao Wang, Jie Zhang   +3 more
wiley   +1 more source

Single-crystalline hole-transporting layers for efficient and stable organic light-emitting devices

Light: Science & Applications
Efficient charge-carrier injection and transport in organic light-emitting devices (OLEDs) are essential to simultaneously achieving their high efficiency and long-term stability.
Gao-Da Ye, Ran Ding, Su-Heng Li, Lei Ni, Shu-Ting Dai, Nian-Ke Chen, Yue-Feng Liu, Runda Guo, Lei Wang, Xian-Bin Li, Bin Xu, Jing Feng   +11 more
doaj   +1 more source