Results 241 to 250 of about 2,646,292 (297)

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

The application of growth factors in bone tissue engineering delivery systems and collaborative innovation strategies. [PDF]

Ann Med
Xu M, Cao H, Wu L.
europepmc   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

Advanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao, Cang‐Man Zhang, Ru‐Jie Yang, Min Ren, Zhuo‐Ling Zhong, Kang‐Hui Wang, Rui‐Xue Hu, Jia‐Yue Liu, Jun‐Yi Zhou, Hou‐Kai Li, Jian‐Bo Wan   +10 more
wiley   +1 more source

Stimuli-Responsive Nanocarriers as Next-Generation on-Demand Drug Delivery Systems for Cancer Therapy: Mechanistic Insights, Trigger Modalities, and Translational Challenges. [PDF]

Pharmaceutics
Alaysereen AAY, Daoud MME, Alhoda MMAMB, Zayer AHA, Deen GR.   +4 more
europepmc   +1 more source

Chitosan-based nanoparticles as a targeted drug delivery system to treat thyroid cancer: A literature review. [PDF]

Medicine (Baltimore)
Alyami HS, Ahmadi NA.
europepmc   +1 more source

Nanomedicine for Cardiac Repair in Heart Failure: From Targeted Delivery to Regenerative Modulation. [PDF]

Int J Nanomedicine
Wang W, Wang Q.
europepmc   +1 more source

Oral Delivery Systems for Food-Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits. [PDF]

Adv Sci (Weinh)
Xu Y, Li F, Zhao R, Shu T, Min W, Zhu BW.   +5 more
europepmc   +1 more source

Autonomous Microrobots for Spatiotemporally Active Therapeutic Delivery and Controlled Release. [PDF]

Cyborg Bionic Syst
Zhong S, Wu A, Bai S, Huang H, Fukuda T, Wang H.   +5 more
europepmc   +1 more source

Recent advances in ultrasound microbubble-mediated gold-based nanomaterials for cancer theranostics. [PDF]

Front Chem
Ma X, Chen X, Li H, Gao J.
europepmc   +1 more source

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Defect Engineering of 2D Semiconductors for Dual Control of Emission and Carrier Polarity

Advances in Materials, 2023
2D transition metal dichalcogenides (TMDCs) are considered as promising materials in post‐Moore technology. However, the low photoluminescence quantum yields (PLQY) and single carrier polarity due to the inevitable defects during material preparation are
Ying Chen, Huawei Liu, Guo-Liang Yu, Chao Ma, Zheyuan Xu, Jinding Zhang, Cheng Zhang, Mingxing Chen, Dong Li, Wei-Hao Zheng, Zi-Yu Luo, Xin Yang, Kaihui Li, Chengdong Yao, Dan-Liang Zhang, Boyi Xu, Jiali Yi, Chen Yi, Bo Li, Hongmei Zhang, Zu-Cheng Zhang, Xiaoli Zhu, Si-Yu Li, Shu-La Chen, Ying Jiang, An-Lian Pan   +25 more
semanticscholar   +1 more source