Results 31 to 40 of about 930,463 (249)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Diffusion-controlled, Size-based Separation of Narrowedly Distributed Suspensions in Pressure-driven Flows Through Microfluidic Bumper Arrays

Chemical Engineering Transactions, 2019
Microfluidic bumper arrays (also referred to as Deterministic Lateral Displacement devices, DLD) have been proposed in the last fifteen years as a simple and effective mean to implement the label-free, size-based separation of a suspension of micrometric-
Stefano Cerbelli
doaj   +1 more source

After Actavis: Seven Ways Forward

, 2015
The Supreme Court’s decision in FTC v. Actavis is one of the most important antitrust decisions in the modern era. This symposium in the Rutgers University Law Review, which accompanied a live conference at the University of San Francisco Law School ...

core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Modification of SnO₂ Electron Transport Layer in Perovskite Solar Cells

Nanomaterials, 2022
Rapid development of the device performance of organic-inorganic lead halide perovskite solar cells (PSCs) are emerging as a promising photovoltaic technology. Current world-record efficiency of PSCs is based on tin oxide (SnO2) electron transport layers
Helen Hejin Park
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

3D dynamic culture of muse cells on a porous gelatin microsphere after magnetic sorting: Achieving high purity proliferation

Regenerative Therapy
Muse cell has become a promising source of cells for disease treatment due to its remarkable characteristics, including stress tolerance, low tumorigenicity, effective homing ability, and differentiation into histocompatibility cells after ...
Zhe Lu, Shifeng Ren, Bingjie Wang, Yajun Zhang, Xiaodong Mu, Zhihui Wang   +5 more
doaj   +1 more source

Anti-Multipath Orthogonal Chirp Division Multiplexing for Underwater Acoustic Communication

IEEE Access, 2020
Multipath due to reflections of the sea surface, seabed, and obstacles, as well as inhomogeneity within the ocean, is an important characteristic of underwater acoustic channels. Mutual interference among multiple paths causes severe amplitude fading and
Peibin Zhu, Xiaomei Xu, Xingbin Tu, Yougan Chen, Yi Tao   +4 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Experiences of family caregivers of children living with thalassaemia-major in Karachi: a phenomenological study

BMJ Public Health
Introduction Thalassaemia major, a global health burden, presents a growing challenge in Pakistan’s strained healthcare system. This study explores how caregivers of children with beta-thalassaemia major navigate healthcare services, aiming to identify ...
Sadaf Altaf, Muhammad Asim, Maliha Baqar, Jawaria Mukhtar Ahmed, Nousheen Pradhan   +4 more
doaj   +1 more source