Results 31 to 40 of about 4,482,895 (292)

Transport proteins (carriers) of mitochondria [PDF]

open access: yesIUBMB Life, 2008
AbstractMitochondria are subcellular structures essential to the aerobic eukaryotic cell. Their role extends much beyond their basic reactions of oxidative phosphorylation. It encompasses the steps critical for cellular metabolic pathways, for apoptosis, and for other processes such as antiviral signaling.
openaire   +2 more sources

Engineering an AB5 Protein Carrier [PDF]

open access: yesScientific Reports, 2018
AbstractThe promise of biologic therapeutics is hindered by the challenge to deliver their activity to biochemically relevant sites within diseased cells. The favourable application of the natural protein carriers of the AB5 toxin family to this challenge has been restricted owing to still unresolved requirements for assembling non-native cargo into ...
Bruce R. Lichtenstein, Birte Höcker
openaire   +5 more sources

The β-casein-resveratrol complex: Physicochemical characteristics and implications for enhanced nutrition [PDF]

open access: yesJournal of the Serbian Chemical Society, 2016
Food proteins have been widely used as carrier materials for the encapsulation and protection of bioactive molecules. Clarification the mechanism of protein-bioactive molecule interaction is important for the development protein-based carrier ...
Cheng Hao   +4 more
doaj   +1 more source

Differentiating carrier protein interactions in biosynthetic pathways using dapoxyl solvatochromism. [PDF]

open access: yesChem Sci
Carrier protein-dependent synthases are ubiquitous enzymes involved both in primary and secondary metabolism. Biocatalysis within these synthases is governed by key interactions between the carrier protein, substrate, and partner enzymes.
Miyada MG   +4 more
europepmc   +2 more sources

Trapping of the Enoyl-Acyl Carrier Protein Reductase–Acyl Carrier Protein Interaction [PDF]

open access: yesJournal of the American Chemical Society, 2016
An ideal target for metabolic engineering, fatty acid biosynthesis remains poorly understood on a molecular level. These carrier protein-dependent pathways require fundamental protein-protein interactions to guide reactivity and processivity, and their control has become one of the major hurdles in successfully adapting these biological machines.
Tallorin, Lorillee   +5 more
openaire   +4 more sources

Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) [PDF]

open access: yes, 2005
Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) is a morphogen with the ability to induce the formation of cartilage and new bone. In the product currently on the market for some special orthopaedic indications, rhBMP-2 is implanted by invasive ...
Schwartz, Daniel
core   +1 more source

Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development

open access: yesmSphere, 2019
Glycoconjugate vaccines are a critical component of the medical arsenal against infectious diseases. This established field continues, however, to experience failures in the clinic.
Fikri Avci   +8 more
doaj   +1 more source

Determination of the Protein-Protein Interactions within Acyl Carrier Protein (MmcB)-Dependent Modifications in the Biosynthesis of Mitomycin

open access: yesMolecules, 2021
Mitomycin has a unique chemical structure and contains densely assembled functionalities with extraordinary antitumor activity. The previously proposed mitomycin C biosynthetic pathway has caused great attention to decipher the enzymatic mechanisms for ...
Dongjin Leng   +7 more
doaj   +1 more source

Subcellular localization of the mosquito sterol carrier protein-2 and sterol carrier protein-x

open access: yesJournal of Lipid Research, 2004
Subcellular distribution of Aedes aegypti sterol carrier protein-2 (AeSCP-2) and AeSCP-x was studied using electron microscopy. In both cultured A. aegypti cells and in the larval midgut, AeSCP-2 was detected mostly in the cytosol, with some labeling ...
Que Lan, Randall J. Massey
doaj   +1 more source

Acyl–Acyl Carrier Protein Desaturases and Plant Biotic Interactions

open access: yesCells, 2021
Interactions between land plants and other organisms such as pathogens, pollinators, or symbionts usually involve a variety of specialized effectors participating in complex cross-talks between organisms.
Sami Kazaz   +2 more
doaj   +1 more source

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