Results 31 to 40 of about 4,482,895 (292)
Transport proteins (carriers) of mitochondria [PDF]
AbstractMitochondria are subcellular structures essential to the aerobic eukaryotic cell. Their role extends much beyond their basic reactions of oxidative phosphorylation. It encompasses the steps critical for cellular metabolic pathways, for apoptosis, and for other processes such as antiviral signaling.
openaire +2 more sources
Engineering an AB5 Protein Carrier [PDF]
AbstractThe promise of biologic therapeutics is hindered by the challenge to deliver their activity to biochemically relevant sites within diseased cells. The favourable application of the natural protein carriers of the AB5 toxin family to this challenge has been restricted owing to still unresolved requirements for assembling non-native cargo into ...
Bruce R. Lichtenstein, Birte Höcker
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The β-casein-resveratrol complex: Physicochemical characteristics and implications for enhanced nutrition [PDF]
Food proteins have been widely used as carrier materials for the encapsulation and protection of bioactive molecules. Clarification the mechanism of protein-bioactive molecule interaction is important for the development protein-based carrier ...
Cheng Hao +4 more
doaj +1 more source
Differentiating carrier protein interactions in biosynthetic pathways using dapoxyl solvatochromism. [PDF]
Carrier protein-dependent synthases are ubiquitous enzymes involved both in primary and secondary metabolism. Biocatalysis within these synthases is governed by key interactions between the carrier protein, substrate, and partner enzymes.
Miyada MG +4 more
europepmc +2 more sources
Trapping of the Enoyl-Acyl Carrier Protein Reductase–Acyl Carrier Protein Interaction [PDF]
An ideal target for metabolic engineering, fatty acid biosynthesis remains poorly understood on a molecular level. These carrier protein-dependent pathways require fundamental protein-protein interactions to guide reactivity and processivity, and their control has become one of the major hurdles in successfully adapting these biological machines.
Tallorin, Lorillee +5 more
openaire +4 more sources
Development of an Aqueous Suspension of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) [PDF]
Recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) is a morphogen with the ability to induce the formation of cartilage and new bone. In the product currently on the market for some special orthopaedic indications, rhBMP-2 is implanted by invasive ...
Schwartz, Daniel
core +1 more source
Glycoconjugate vaccines are a critical component of the medical arsenal against infectious diseases. This established field continues, however, to experience failures in the clinic.
Fikri Avci +8 more
doaj +1 more source
Mitomycin has a unique chemical structure and contains densely assembled functionalities with extraordinary antitumor activity. The previously proposed mitomycin C biosynthetic pathway has caused great attention to decipher the enzymatic mechanisms for ...
Dongjin Leng +7 more
doaj +1 more source
Subcellular localization of the mosquito sterol carrier protein-2 and sterol carrier protein-x
Subcellular distribution of Aedes aegypti sterol carrier protein-2 (AeSCP-2) and AeSCP-x was studied using electron microscopy. In both cultured A. aegypti cells and in the larval midgut, AeSCP-2 was detected mostly in the cytosol, with some labeling ...
Que Lan, Randall J. Massey
doaj +1 more source
Acyl–Acyl Carrier Protein Desaturases and Plant Biotic Interactions
Interactions between land plants and other organisms such as pathogens, pollinators, or symbionts usually involve a variety of specialized effectors participating in complex cross-talks between organisms.
Sami Kazaz +2 more
doaj +1 more source

