Results 141 to 150 of about 6,901,957 (346)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

An AIEgen-Based Carrier Enables Efficient Cytosolic Delivery of Bioactive Proteins

International Journal of Nanomedicine
Yu Yang,1– 3,* Huixia Jia,1– 3,* Lin Yang,4 Benzhao He,4 Ke Zhang,1– 3 He Liu1– 3 1Department of Systems Science, Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, Guangdong, 519087, People’s Republic of China ...
Yang Y, Jia H, Yang L, He B, Zhang K, Liu H   +5 more
doaj  

Sequential Extraction Transformation of Brown Onion Skin into Cellulose-Based Enzyme Immobilization Carrier

Applied Sciences
The present study aimed to design a process of brown onion skin transformation by sequential extraction to a cellulose-based immobilization carrier, along with detailed analysis of obtained extracts, pointing to approaching a “zero-waste” model of ...
Mirna Brekalo, Marta Ostojčić, Marija Stjepanović, Blanka Bilić Rajs, Petra Matić, Stjepan Šarić, Jovana Stanojev, Krunoslav Aladić, Lidija Jakobek Barron, Stela Jokić, Igor Djerdj, Ivica Strelec, Sandra Budžaki   +12 more
doaj   +1 more source

Heterologous Expression, Purification, and Characterization of Type II Polyketide Synthase Acyl Carrier Proteins. [PDF]

Methods Mol Biol, 2022
Hamrick GS, Londergan CH, Charkoudian LK.   +2 more
europepmc   +1 more source

Manipulating Protein-Protein Interactions in Nonribosomal Peptide Synthetase Type II Peptidyl Carrier Proteins.

Biochemistry, 2017
Matt J. Jaremko, D. J. Lee, Ashay Patel, Victoria Winslow, S. Opella, J., Andrew McCammon, M. Burkart   +7 more
semanticscholar   +1 more source

Intracellular Protein Delivery Systems Formed by Noncovalent Bonding Interactions between Amphipathic Peptide Carriers and Protein Cargos

, 2010
Seong Loong Lo, Shu Wang
openalex   +2 more sources

Regioselectivity of the Thunbergia alata Δ6-16:0-acyl carrier protein desaturase by molecular dynamics [PDF]

, 2023
Marcel D. Baer, Simone Raugei, John Shanklin   +2 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Immune Response to Conjugates of Fragments of the Type K9 Capsular Polysaccharide of Acinetobacter baumannii with Carrier Proteins. [PDF]

Microbiol Spectr, 2022
Rudenko N, Karatovskaya A, Zamyatina A, Shepelyakovskaya A, Semushina S, Brovko F, Shpirt A, Torgov V, Kolotyrkina N, Zinin A, Kasimova A, Perepelov A, Shneider M, Knirel Y.   +13 more
europepmc   +1 more source

Enzymatic Desaturation of Stearyl Acyl Carrier Protein

, 1966
Jun Nagai, Konrad E. Bloch
openalex   +1 more source