Results 161 to 170 of about 397,916 (259)

Divergent Tandem Acyl Carrier Proteins Necessitate In-Series Polyketide Processing in the Leinamycin Family. [PDF]

Angew Chem Int Ed Engl
Phillips AP, Winter AJ, Hooper CM, Williams C, Crosby J, Willis CL, Crump MP.   +6 more
europepmc   +1 more source

Apolipoproteins, as the carrier proteins for lipids, are involved in the development of breast cancer. [PDF]

Clin Transl Oncol, 2020
Zhou Y, Luo G.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Exploring the compatibility of phosphopantetheinyl transferases with acyl carrier proteins spanning type II polyketide synthase sequence space. [PDF]

J Ind Microbiol Biotechnol
Bifendeh ALN, Hsu KK, McBride CM, Ferguson CM, Baumann ER, Capcha-Rodriguez D, Chen X, Chery B, Chihade MM, Umpierre PD, Evans T, Everett CH, Faheem SF, Garrett OD, Gottesfeld AR, Gupta IG, Haas JD, Haupt TA, Katz J, Kim S, Langer M, Le V, Li KK, Zhao B, Lin S, Mabry KN, Malkov A, Marquis AT, McDonnell KR, Min K, Mostaghim NB, Nichols KM, Osbaldeston RA, Phan TT, Ponte AT, Qaraqe T, Rosas BS, Smith CS, Smith LE, Smith MW, Soll ACR, Sotero GR, Thornberry IE, Tran K, Vo QK, Yoc-Bautista MG, Young M, Zukowski KA, Fairman R, Wodzanowski KA, Herrera MA, Cho YI, Charkoudian LK.   +52 more
europepmc   +1 more source

Comparison of carrier proteins to conjugate malaria transmission blocking vaccine antigens, Pfs25 and Pfs230. [PDF]

Vaccine, 2020
Scaria PV, Chen BB, Rowe CG, Alani N, Muratova OV, Barnafo EK, Lambert LE, Zaidi IU, Lees A, Rausch KM, Narum DL, Duffy PE.   +11 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Mutagenesis Supports AlphaFold Prediction of How Modular Polyketide Synthase Acyl Carrier Proteins Dock With Downstream Ketosynthases. [PDF]

Proteins
Hirsch M, Desai RR, Annaswamy S, Keatinge-Clay AT.   +3 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Distal peptide elongation by a protease-like ligase and two distinct carrier proteins.

Chem
Gude F, Bohne A, Dell M, Franke J, Dunbar KL, Groll M, Hertweck C.   +6 more
europepmc   +1 more source

Effects of long-term dehydration and quick rehydration on the camel kidney: pathological changes and modulation of the expression of solute carrier proteins and aquaporins. [PDF]

BMC Vet Res
Damir HA, Ali MA, Adem MA, Amir N, Ali OM, Tariq S, Adeghate E, Greenwood MP, Lin P, Alvira-Iraizoz F, Gillard B, Murphy D, Adem A.   +12 more
europepmc   +1 more source