Results 161 to 170 of about 8,126,655 (341)

Chimeric carrier proteins for targeted delivery of tumor antigens to professional antigen presenting cells [PDF]

, 2007
Tumor-specific T lymphocytes can be regarded as a highly effective mechanism for tumor rejection. A substantial number of T-cell defined tumor antigens including mutated oncoproteins and differentiation antigens have been identified.
Kursar, Mischo, Mittrücker, Hans-Willi, Rohrbach, Florian, Wels, Winfried S., Weth, Robert   +4 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Of its five acyl carrier proteins, only AcpP1 functions in Ralstonia solanacearum fatty acid synthesis. [PDF]

Front Microbiol, 2022
Yin Y, Li R, Liang WT, Zhang WB, Hu Z, Ma JC, Wang HH.   +6 more
europepmc   +1 more source

Manipulating Protein-Protein Interactions in Nonribosomal Peptide Synthetase Type II Peptidyl Carrier Proteins.

Biochemistry, 2017
Matt J. Jaremko, D. J. Lee, Ashay Patel, Victoria Winslow, S. Opella, J., Andrew McCammon, M. Burkart   +7 more
semanticscholar   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Acyl Carrier Protein

Journal of Biological Chemistry, 1969
Gary L. Powell, John Elovson, P. Roy Vagelos   +2 more
  +4 more sources

An AIEgen-Based Carrier Enables Efficient Cytosolic Delivery of Bioactive Proteins

International Journal of Nanomedicine
Yu Yang,1– 3,* Huixia Jia,1– 3,* Lin Yang,4 Benzhao He,4 Ke Zhang,1– 3 He Liu1– 3 1Department of Systems Science, Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, Guangdong, 519087, People’s Republic of China ...
Yang Y, Jia H, Yang L, He B, Zhang K, Liu H   +5 more
doaj  

Anammox Bacterial S-Adenosyl-l-Methionine Dependent Methyltransferase Crystal Structure and Its Interaction with Acyl Carrier Proteins. [PDF]

Int J Mol Sci, 2023
Uegaki T, Takei T, Yamaguchi S, Fujiyama K, Sato Y, Hino T, Nagano S.   +6 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Heterologous Expression, Purification, and Characterization of Type II Polyketide Synthase Acyl Carrier Proteins. [PDF]

Methods Mol Biol, 2022
Hamrick GS, Londergan CH, Charkoudian LK.   +2 more
europepmc   +1 more source