Journal of Lipid Research, 2016 Sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) are bioactive signaling lysophospholipids that activate specific G protein-coupled receptors on the cell surface triggering numerous biological events.
Jonathan K. Fleming +3 more
doaj
Experimental Data Confirm Carrier-Cascade Model for Solid-State Conductance across Proteins [PDF]
arXivThe finding that electronic conductance across ultra-thin protein films between metallic electrodes remains nearly constant from room temperature to just a few degrees Kelvin has posed a challenge. We show that a model based on a generalized Landauer formula explains the nearly constant conductance and predicts an Arrhenius-like dependence for low ...
arxiv
Beyond esterase-like activity of serum albumin. Histidine-(nitro)phenol radical formation in conversion cascade of p-nitrophenyl acetate and the role of infrared light [PDF]
arXiv, 2018 Serum albumin, recognized mainly for its capacity to act as a carrier protein for many compounds, can also actively transform some organic molecules. As a starting point in this study we consider esterase-like activity of bovine serum albumin (BSA) toward p-nitrophenyl acetate (p-NPA).
arxiv
Anammox Bacterial S-Adenosyl-l-Methionine Dependent Methyltransferase Crystal Structure and Its Interaction with Acyl Carrier Proteins. [PDF]
Int J Mol Sci, 2023 Uegaki T +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Landscape phage, phage display, stripped phage, biosensors, detection, affinity reagent, nanotechnology, Salmonella typhimurium, Bacillus anthracis [PDF]
Dans European Nano Systems Worshop - ENS 2005, Paris : France
(2005), 2007 Filamentous phage, such as fd used in this study, are thread-shaped bacterial viruses. Their outer coat is a tube formed by thousands equal copies of the major coat protein pVIII. We constructed libraries of random peptides fused to all pVIII domains and selected phages that act as probes specific for a panel of test antigens and biological threat ...
arxiv
Evidence for Non-Essential Salt Bridges in the M-Gates of Mitochondrial Carrier Proteins. [PDF]
Int J Mol Sci, 2022 Miniero DV +4 more
europepmc +1 more source
Clinical significance of stratifying prostate cancer patients through specific circulating genes
Molecular Oncology, EarlyView.We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian +12 more
wiley +1 more source
T300A GENETIC POLYMORPHISM: a susceptibility factor for Crohn’s disease?
Arquivos de GastroenterologiaContextCrohn’s disease is characterized by a chronic and debilitating inflammatory disorder of the gastrointestinal tract. Several factors may contribute to its development.
Bruno Lorenzo SCOLARO +6 more
doaj +1 more source
A Clinical Trial of Entolimod a TLR-5 Adjuvant for Vaccines Using Diphtheria or Tetanus as Carrier Proteins. [PDF]
Vaccines (Basel), 2022 Kosten TR +3 more
europepmc +1 more source