Results 171 to 180 of about 560,339 (380)

A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay

open access: yesJournal of Lipid Research, 2016
Sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) are bioactive signaling lysophospholipids that activate specific G protein-coupled receptors on the cell surface triggering numerous biological events.
Jonathan K. Fleming   +3 more
doaj  

Experimental Data Confirm Carrier-Cascade Model for Solid-State Conductance across Proteins [PDF]

open access: yesarXiv
The finding that electronic conductance across ultra-thin protein films between metallic electrodes remains nearly constant from room temperature to just a few degrees Kelvin has posed a challenge. We show that a model based on a generalized Landauer formula explains the nearly constant conductance and predicts an Arrhenius-like dependence for low ...
arxiv  

Beyond esterase-like activity of serum albumin. Histidine-(nitro)phenol radical formation in conversion cascade of p-nitrophenyl acetate and the role of infrared light [PDF]

open access: yesarXiv, 2018
Serum albumin, recognized mainly for its capacity to act as a carrier protein for many compounds, can also actively transform some organic molecules. As a starting point in this study we consider esterase-like activity of bovine serum albumin (BSA) toward p-nitrophenyl acetate (p-NPA).
arxiv  

Of its five acyl carrier proteins, only AcpP1 functions in Ralstonia solanacearum fatty acid synthesis. [PDF]

open access: yesFront Microbiol, 2022
Yin Y   +6 more
europepmc   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Landscape phage, phage display, stripped phage, biosensors, detection, affinity reagent, nanotechnology, Salmonella typhimurium, Bacillus anthracis [PDF]

open access: yesDans European Nano Systems Worshop - ENS 2005, Paris : France (2005), 2007
Filamentous phage, such as fd used in this study, are thread-shaped bacterial viruses. Their outer coat is a tube formed by thousands equal copies of the major coat protein pVIII. We constructed libraries of random peptides fused to all pVIII domains and selected phages that act as probes specific for a panel of test antigens and biological threat ...
arxiv  

Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. [PDF]

open access: yes, 1984
The present study examines the ability of hapten-specific murine splenic B lymphocytes to present hapten-proteins to carrier-specific T cell hybridomas.
Abbas, AK, Benacerraf, B, Rock, KL
core  

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

T300A GENETIC POLYMORPHISM: a susceptibility factor for Crohn’s disease?

open access: yesArquivos de Gastroenterologia
ContextCrohn’s disease is characterized by a chronic and debilitating inflammatory disorder of the gastrointestinal tract. Several factors may contribute to its development.
Bruno Lorenzo SCOLARO   +6 more
doaj   +1 more source

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