Results 181 to 190 of about 570,690 (336)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Protocol for the purification, analysis, and handling of acyl carrier proteins from type I fatty acid and polyketide synthases. [PDF]

STAR Protoc
Gusenda C, Berlage S, Burkhart I, Chagot B, Weissman KJ, Schwalbe H, Grininger M.   +6 more
europepmc   +1 more source

Rat adrenal corticosteroidogenesis; Effect of ACTH, cycloheximide and sterol carrier protein.

, 1977
SHOGO ICHII, Noriko Murakami, Ryuichi Sakata   +2 more
openalex   +2 more sources

The function of acyl carrier protein in the synthesis of membrane-derived oligosaccharides does not require its phosphopantetheine prosthetic group. [PDF]

, 1987
Hélène Therisod, Eugene P. Kennedy
openalex   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

The impact of solute carrier proteins on disrupting substance regulation in metabolic disorders: insights and clinical applications. [PDF]

Front Pharmacol
Du J, Shen M, Chen J, Yan H, Xu Z, Yang X, Yang B, Luo P, Ding K, Hu Y, He Q.   +10 more
europepmc   +1 more source

Apolipoproteins, as the carrier proteins for lipids, are involved in the development of breast cancer. [PDF]

Clin Transl Oncol, 2020
Zhou Y, Luo G.
europepmc   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Elucidating the role of carrier proteins in cytokine stabilization within double emulsion-based polymeric nanoparticles. [PDF]

Bioeng Transl Med
Rhodes ER, Day NB, Aldrich EC, Wyatt Shields C, Sprenger KG.   +4 more
europepmc   +1 more source

Intracellular and intramitochondrial sorting of precursor proteins [PDF]

, 1987
Neupert, Walter, Ozawa, Takayuki, Papa, S., Schwaiger, Martin   +3 more
core   +1 more source