Results 201 to 210 of about 9,648,893 (334)

Probing the structure and function of acyl carrier proteins to unlock the strategic redesign of type II polyketide biosynthetic pathways. [PDF]

J Biol Chem, 2021
Sulpizio A, Crawford CEW, Koweek RS, Charkoudian LK.   +3 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Reading: Roch Carrier

, 1991
In this audiovisual recording from Friday, March 22, 1991, as part of the 22nd Annual UND Writers Conference: “The Literatures of Canada,” Roch Carrier reads a selection of his work.
Carrier, Roch
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Protocol for the purification, analysis, and handling of acyl carrier proteins from type I fatty acid and polyketide synthases. [PDF]

STAR Protoc
Gusenda C, Berlage S, Burkhart I, Chagot B, Weissman KJ, Schwalbe H, Grininger M.   +6 more
europepmc   +1 more source

Identification of Candidate Carrier Proteins for Surface Display on Lactococcus lactis by Theoretical and Experimental Analyses of the Surface Proteome

Applied and Environmental Microbiology, 2010
A. Berlec, Petra Zadravec, Z. Jevnikar, B. Štrukelj   +3 more
semanticscholar   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Elucidating the role of carrier proteins in cytokine stabilization within double emulsion-based polymeric nanoparticles. [PDF]

Bioeng Transl Med
Rhodes ER, Day NB, Aldrich EC, Wyatt Shields C, Sprenger KG.   +4 more
europepmc   +1 more source

Cellular uptake of steroid carrier proteins--mechanisms and implications.

Molecular and Cellular Endocrinology, 2010
T. Willnow, A. Nykjaer
semanticscholar   +1 more source