Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu+4 more
wiley +1 more source
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux. [PDF]
Bosdriesz E+5 more
europepmc +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns+2 more
wiley +1 more source
Molecular Cross-Talk between Nonribosomal Peptide Synthetase Carrier Proteins and Unstructured Linker Regions. [PDF]
Harden BJ, Frueh DP.
europepmc +1 more source
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran+3 more
wiley +1 more source
Motor protein independent binding of endocytic carrier vesicles to microtubules in vitro.
John R. Scheel, T E Kreis
openalex +1 more source
New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis. [PDF]
Kittilä T+3 more
europepmc +1 more source
Enhanced production of polyunsaturated fatty acids by enzyme engineering of tandem acyl carrier proteins. [PDF]
Hayashi S+4 more
europepmc +1 more source
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Regulation of sterol carrier protein-2 gene expression in rat liver and small intestine
CL Baum, Selena Kansal, NO Davidson
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