Results 81 to 90 of about 560,339 (380)

Mitochondrial import receptors for precursor proteins [PDF]

, 1991
The specific targeting of precursor proteins synthesized in the cytosol to various cell organelles is a central aspect of intracellular protein traffic. Several hundred different proteins are imported from the cytosol into the mitochondria.
Attardi, Baker, Deshaies, Gillespie, Hartl, Hines, Horwich, Hwang, Kang, Kiebler, Klingenberg, Meyer, Murakami, Murakami, Murakami, Ono, Pain, Pfaller, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Riezman, Roise, Rosenberg, Schnell, Sheffield, So¨llner, So¨llner, Steger, Vestweber, Wickner   +34 more
core   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Epididymosomes: transfer of fertility-modulating proteins to the sperm surface

Asian Journal of Andrology, 2015
A variety of glycosylphosphatidylinositol (GPI)-linked proteins are acquired on spermatozoa from epididymal luminal fluids (ELF) during sperm maturation.
Patricia A Martin-DeLeon
doaj   +1 more source

Diseases Caused by Mutations in Mitochondrial Carrier Genes SLC25: A Review

Biomolecules, 2020
In the 1980s, after the mitochondrial DNA (mtDNA) had been sequenced, several diseases resulting from mtDNA mutations emerged. Later, numerous disorders caused by mutations in the nuclear genes encoding mitochondrial proteins were found. A group of these
Ferdinando Palmieri, Pasquale Scarcia, Magnus Monné   +2 more
doaj   +1 more source

Biochemically altered human erythrocytes as a carrier for targeted delivery of primaquine: an in vitro study [PDF]

Arch. Pharm. Res. (2011) 34: 563, 2019
The aim of this study was to investigate human erythrocytes as a carrier for targeted drug delivery of primaquine (PQ). The process of PQ loading in human erythrocytes, as well as the effect of PQ loading on the oxidative status of erythrocytes, was also studied.
arxiv   +1 more source

Cell-Free Synthesis of the Mitochondrial ADP/ATP Carrier Protein of Neurospora crassa [PDF]

, 1979
ADP/ATP carrier protein was synthesized in heterologous cell-free systems programmed with Neurospora poly(A)-containing RNA and homologous cell-free systems from Neurospora.
Allen E. H., Aviv H., Blomback B., Cassio D., Dubnoff J. S., Fraser T. H., Hackenberg H., Hallermayer G., Harmey M. A., Inouye S., Klingenberg M., Korb H., Laemmli U. K., Leaver C. J., Lodish H. F., Maccechini M.-L., Marahiel M. A., Michel R., Palmiter R. D., Pelham H. R. B., Roberts B. E., Scheele G., Sebald W., Stewart J. W., Vignais P. V., Zitomer R. S.   +25 more
core   +1 more source

Acyl Carrier Protein

Journal of Biological Chemistry, 1973
Abstract A number of analogues of Escherichia coli apo-acyl carrier protein (apo-ACP) have been synthesized by the solid phase method. A standard isolation procedure was used for all analogues. This involved cleavage from the solid support and deprotection by treatment of the peptide-resin with hydrogen bromide and trifluoroacetic acid. The product was
Garland R. Marshall, P. Roy Vagelos, William S. Hancock   +2 more
openaire   +3 more sources

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

Protein insertion into the inner membrane of mitochondria: routes and mechanisms

FEBS Open Bio
The inner membrane of mitochondria contains hundreds of different integral membrane proteins. These proteins transport molecules into and out of the matrix, they carry out multifold catalytic reactions and they promote the biogenesis or degradation of ...
Büsra Kizmaz, Annika Nutz, Annika Egeler, Johannes M. Herrmann   +3 more
doaj   +1 more source

Assembly and Transfer of Iron–Sulfur Clusters in the Plastid

Frontiers in Plant Science, 2018
Iron-Sulfur (Fe-S) clusters and proteins are essential to many growth and developmental processes. In plants, they exist in the plastids, mitochondria, cytosol, and nucleus.
Yan Lu
doaj   +1 more source