Results 61 to 70 of about 1,207,145 (299)

Active Electromagnetic Clutch for Crankshaft Decoupling from a Belt Drive System

Applied Sciences
This work presents a novel electromagnetic clutch installed on the crankshaft pulley to decouple the internal combustion engine from the front-end accessory drive of a P0 hybrid electric vehicle. The objective is to supply the air conditioning compressor
Luis M. Castellanos Molina, Renato Galluzzi, Shailesh Hegde, Angelo Bonfitto, Nicola Amati, Andrea Tonoli, Walter Ventura   +6 more
doaj   +1 more source

Covariate-assisted ranking and screening for large-scale two-sample inference [PDF]

, 2019
Two-sample multiple testing has a wide range of applications. The conventionalpractice first reduces the original observations to a vector of p-values and then chooses a cutoffto adjust for multiplicity.
Cai, T. Tony, Sun, Wenguang, Wang, Weinan   +2 more
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Standoff Detection via Single-Beam Spectral Notch Filtered Pulses

, 2011
We demonstrate single-beam coherent anti-Stokes Raman spectroscopy (CARS), for detecting and identifying traces of solids, including minute amounts of explosives, from a standoff distance (>50 m) using intense femtosecond pulses.
Adi Natan, Jonathan M. Levitt, Leigh Graham, National Research Council, Ori Katz, Yaron Silberberg   +5 more
core   +1 more source

Company Cars and Household Car Choices

SSRN Electronic Journal
Tax systems that favour company cars for personal use could cause households to have more cars. It could also affect the choice of fuel type. We investigate the relationship between household car choices and access to a company car through a difference-in-differences design using Norwegian microdata.
Gøril L. Andreassen, Askill Harkjerr Halse   +1 more
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Nanoplasmonic SERS on fidget spinner for digital bacterial identification

Microsystems & Nanoengineering
Raman spectroscopy offers non-destructive and highly sensitive molecular insights into bacterial species, making it a valuable tool for detection, identification, and antibiotic susceptibility testing.
Mamata Karmacharya, Issac Michael, Jiyun Han, Elizabeth Maria Clarissa, Oleksandra Gulenko, Sumit Kumar, Yoon-Kyoung Cho   +6 more
doaj   +1 more source

Shunting freight cars with own power units [PDF]

, 2010
In this paper it is shown that shunting freight cars can be simplified significantly if the freight cars have their own power unit.
Dahlhaus, Elias
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source