Results 41 to 50 of about 115,107 (269)
Journal of Engineered Fibers and FabricsUsing ABAQUS software as a tool and 225/60R18 tire as the research object, a finite element model of the tire was established and longitudinal slip simulation was conducted based on the completion of longitudinal slip and rubber material tests.
Jun-Ling Meng +5 more
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Annals of HematologyChimeric antigen receptor (CAR) therapies have demonstrated remarkable clinical efficacy in hematological malignancies, validating their therapeutic potential. However, challenges such as therapeutic resistance and limited accessibility hinder their broader application.
Zhang, Yiling +3 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Light‐Driven, Dynamic Assembly of Micron‐To‐Centimeter Parts, Micromachines and Microbot Swarms
Advanced ScienceThis work describes light‐driven assembly of dynamic formations and functional particle swarms controlled by appropriately programmed light patterns. The system capitalizes on the use of a fluidic bed whose low thermal conductivity assures that light ...
Konstantin Polev +7 more
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World Electric Vehicle JournalAs the global transition toward carbon neutrality accelerates, the sustainability of power electronics has received growing attention from both academia and industry.
Chi Zhang, Riccardo Negri
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Review of Radical Political Economics, 2015 This paper discusses the centrality of the automobile to experiencing modern life. Access to a car is considered essential to access vital services and, as such, automobile usage plays a crucial role in commoning. However, this is said to draw lines of inclusion and exclusion premised on financial status, which particularly excludes those in rural ...
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Transportation Research Interdisciplinary Perspectives, 2020 Automated Driver Assistance Systems (ADAS), which aim to enhance safety and comfort while driving, are becoming increasingly popular in vehicles today. However, ADAS are not yet operative in every situation due to technical limitations, and therefore do ...
Fjollë Novakazi +3 more
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