Results 31 to 40 of about 241,740 (317)

Research on the Development Path of Urban Rail Transit Traction Power Supply System Based on Foreign Experience

open access: yesChengshi guidao jiaotong yanjiu
[Objective] In the context of the current urban rail transit towards intelligent,green and low-carbon development, upgrading the traction power supply system, the "heart" of urban rail transit, is of crucial importance for realizing the green and smart ...
HU Ji, LING Chen, SU Jingqi, LIU Shuo
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Company Cars and Household Car Choices

open access: yesSSRN Electronic Journal
Tax systems that favour company cars for personal use could cause households to have more cars. It could also affect the choice of fuel type. We investigate the relationship between household car choices and access to a company car through a difference-in-differences design using Norwegian microdata.
Gøril L. Andreassen   +1 more
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Ground effect aerodynamics of racing cars

open access: yes, 2006
We review the progress made during the last thirty years on ground effect aerodynamics associated with race cars, in particular open wheel race cars.
Zhang, Xin   +5 more
core   +1 more source

Adaptive Determination of Optimum Switching Frequency in SiC-PWM-Based Motor Drives: A Speed-Dependent Core Loss Correction Approach

open access: yesIEEE Open Journal of the Industrial Electronics Society
This study focuses on identifying the optimal switching frequency for silicon-carbide (SiC)-based motor drives across a wide range of operating conditions using a loss minimization strategy. The results are then compared with those of traditional silicon-
Sepideh Amirpour   +3 more
doaj   +1 more source

Seasonal variations of microbes in particulate matter obtained from Dhaka City in Bangladesh

open access: yesEnvironmental Pollutants & Bioavailability, 2021
The present study, for the first time, evaluated the seasonal variation of PM10-associated bacterial and fungal concentrations at four locations (CARS premises, Doyel Chattar, Postogola, and Chittagong Road) in Dhaka, Bangladesh.
Jahan-E- Gulshan   +7 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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