Results 141 to 150 of about 86,499 (264)

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Mechanobiology-based strategies for the maturation of biofabricated cartilage constructs. [PDF]

Front Bioeng Biotechnol
López-González I, Campillo N, Baena JM.   +2 more
europepmc   +1 more source

Behavioral Incentives for Exercise and Intra‐Articular Glucocorticoids for Knee Osteoarthritis: Results From a Factorially Designed Pragmatic Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker, Katherine D. Wysham, Mercedes Quinones, Bryant R. England, Kaitian Jin, Marianna Olave, Sarah Wetzel, Rachel L. Gillcrist, Criswell Lavery, Natalie Keller, Bridget Kramer, Bibianna Ateh, Hannah Brubeck, Daniel K. White, Alexis Ogdie, Rui Xiao, Tuhina Neogi, Carla R. Scanzello   +17 more
wiley   +1 more source

Optimal management of giant cell tumor in the tibial plateau: A case report on curettage and cement reinforcement. [PDF]

Radiol Case Rep
Mouawad J, Honeine MO, Sarkis C, Jamaleddine Y, Hajjar S, Assi C, Bayoud W.   +6 more
europepmc   +1 more source

Autoreactivity Versus Autoimmunity: Characteristics of Autoantigen‐Specific CD4 T Cells in Rheumatoid Arthritis and Health

Arthritis &Rheumatology, EarlyView.
Objective CD4 T cells specific for citrullinated (cit) peptides are key players in rheumatoid arthritis (RA) immunopathogenesis. Characterizing these cells and identifying features of healthy and RA‐associated autoreactivity will provide valuable insight into disease mechanisms and form the basis of immune state biomarkers to facilitate the next ...
James A. Stanway, Daniel Peters, Helen Waller, Jeremy Lakey, Henrique De Paula Lemos, Kristian Williams, Abbie Degnan, Julie Diboll, Abdul Mannan Baru, David Tough, Arthur G. Pratt, Catharien M.U. Hilkens, Amy E. Anderson, John D. Isaacs   +13 more
wiley   +1 more source

Evaluating therapeutic efficacy of iopanoic acid in a DMM-induced osteoarthritis mouse model and osteochondral lesioned human explants. [PDF]

Osteoarthr Cartil Open
Sayedipour SS, Mazzini G, Tuerlings M, Nikkels J, Koedam M, Cruz LJ, Mahdad R, de Weerd L, van der Eerden B, Ramos YF, Meulenbelt I.   +10 more
europepmc   +1 more source

Student‐identified barriers to histology learning and the perceived value of coloring as a multimodal educational strategy

Anatomical Sciences Education, EarlyView.
Abstract Histology is a visually complex and cognitively demanding subject often perceived as abstract, memorization‐heavy, and disconnected from clinical practice. Despite its foundational importance, histology is frequently under‐emphasized relative to gross anatomy and lacks interactive, multimodal resources tailored to its unique challenges.
Anika Knowles, Karen Pinder, Tamara A. Franz‐Odendaal   +2 more
wiley   +1 more source

Accuracy of Computed Tomography in Diagnosing Temporomandibular Joint Osteoarthritis Relative to Histopathological Findings-An Ex Vivo Study of 41 Horses. [PDF]

Animals (Basel)
Jasiński T, Zdrojkowski Ł, Turek B, Kaczorowski M, Pawliński B, Brehm W, Domino M.   +6 more
europepmc   +1 more source

Lateral Extra‐articular Tenodesis Utilizing Modified Ellison Technique With Knotless Anchor Fixation

Arthroscopy Techniques, EarlyView.
Abstract Lateral extra‐articular tenodesis (LET) to augment anterior cruciate ligament reconstruction significantly reduces graft failure rates. Although there are many techniques for lateral extra‐articular tenodesis, the modified Ellison technique provides numerous advantages as a distally fixed construct, including dynamic rotational stability ...
Joseph M. Sliepka, Natalie K. Kucirek, Alan L. Zhang   +2 more
wiley   +1 more source

Intra-articular injection of allogeneic canine adipose-derived stem cell enriched secretome in dogs undergoing tibial plateau leveling osteotomy: a prospective double-blind and randomized pilot trial. [PDF]

Vet Res Commun
Carrera ALC, Minto BW, Alcântara BM, Previtali DAC, Faustino RCS, Tavares ABL, Doiche DP, Nogueira C, Brunel HSS, Pereira RW, Alievi MM, Dias LGGG, Malard PF.   +12 more
europepmc   +1 more source