Results 241 to 250 of about 151,261 (309)

Non‐Porous Hydrogel Scaffolds for Locoregional Chemotherapy: A One‐Pot Synthesis Approach

Macromolecular Materials and Engineering, EarlyView.
This hydrogel scaffold with tunable mechanical, water retention, degradation, and drug release properties is obtained by polymerizing the hydrophilic OEGMEMA monomer in the presence of PLGA and DOX under concentrated conditions. Its non‐porous structure provides diffusion‐based drug release, while extended drug release is possible by incorporating PLGA.
Sadik Kaga, Gizem Fatma Erguner
wiley   +1 more source

From cells to clinic: Single-cell transcriptomics shaping the future of orthopedics. [PDF]

J Orthop Translat
Wang Q, Huang M, Guo JJ.
europepmc   +1 more source

Antifouling Coatings Inspired by Biological Templates

Macromolecular Rapid Communications, EarlyView.
The polymeric coatings developed using biological templates combine antifouling properties of polymers with mechanical properties of micro‐ and nano‐particles yielding contact active, foulant releasable, and stimuli responsive materials with superior antifouling performance and demonstrate several applications in the marine environment, as delivery ...
Catherine Doyle, Marya Ahmed
wiley   +1 more source

Repetitive Compressive Loading Downregulates Mitochondria Function and Upregulates the Cartilage Matrix Degrading Enzyme MMP-13 Through the Coactivation of NAD-Dependent Sirtuin 1 and Runx2 in Osteoarthritic Chondrocytes. [PDF]

Int J Mol Sci
Takemoto M, Sugishita Y, Takahashi-Suzuki Y, Fujiya H, Niki H, Yudoh K.   +5 more
europepmc   +1 more source

Friction and Wear Characterizations in Electrospun Nanofibrous Scaffolds for Cartilage Engineering

Nano Select, EarlyView.
Articular cartilage (AC)‐engineered electrospun scaffolds have experienced a surge in interest in publication in recent years. However, nanofiber frictional properties are poorly explored in the existing literature. We evaluated the effect of countersurface, speed, and hydrophilicity on nanofibers.
André Mathias Souza Plath, Mohammad Alinezhadfar, Stephen J. Ferguson   +2 more
wiley   +1 more source

Glenoid Microfracture With or Without Arthroscopic Rotator Cuff Repair: Similar Rates of Return to Full Duty and Patient-Reported Outcome Measures Among Active-Duty Military Patients. [PDF]

Orthop J Sports Med
Sandler AB, Scanaliato JP, Thompson A, Green CK, Corning ED, Clark D, Jones EW, Parnes N.   +7 more
europepmc   +1 more source

Multi‐Walled Carbon Nanotube Reinforced Polyacrylamide‐Acrylic Acid Nanocomposite Hydrogels With Superior Mechanical and Tribological Performance as Focal Cartilage Substitute

Polymer Engineering &Science, EarlyView.
ABSTRACT Though mimicking cartilage's structure, hydrogels often present weak mechanical performance, which limits their use in cartilage repair. Here, nanocomposite hydrogel was synthesized by incorporating multi‐walled carbon nanotubes (CNTs) into a covalently bonded polyacrylamide/polyacrylic acid (PAAm/PAAc) hydrogel. Fourier transform infrared and
Yusuf Kanca, Rabia Özdemir, Daniele Dini, Bengi Özkahraman   +3 more
wiley   +1 more source

Solute transport from synovial fluid to articular cartilage and subchondral bone at different stages of osteoarthritis in a live mouse model. [PDF]

J Orthop Translat
Chen M, Yang Y, Cui M, Wang B.
europepmc   +1 more source

Bimodal Dissolving Microneedles with Nanoparticle Coating and Encapsulation for Extended Dual‐Drug Delivery

Small, EarlyView.
A novel bimodal coated‐dissolving microneedle system is developed for extended transdermal delivery of diclofenac and dexamethasone nanoparticles. The formulation enables high drug loading, efficient skin penetration, and sustained release over 72 h, offering a minimally invasive, self‐administered therapy to improve osteoarthritis treatment by ...
Mingshan Li, Akmal H.B. Sabri, Nuoya Qin, Ke Peng, Marco Abbate, Alejandro J. Paredes, Helen O McCarthy, Lalitkumar K. Vora, Ryan F. Donnelly   +8 more
wiley   +1 more source

The mitochondrial protectant SS31 optimized decellularized Wharton's jelly scaffold improves allogeneic chondrocyte implantation-mediated articular cartilage repair. [PDF]

J Orthop Translat
Wang C, Li H, Li F, Yang Y, Xu Z, Gao T, Li R, Zhang R, Mu Y, Guo Z, Guo Q, Liu S.   +11 more
europepmc   +1 more source