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Journal of the American Academy of Orthopaedic Surgeons, 2003
Articular cartilage is a complex tissue maintained by chondrocytes, which undergo metabolic changes as a result of aging, disease, and injury. These changes may hinder tissue maintenance and repair, resulting in accelerated loss of articular surface and leading to end-stage arthritis.
Regis J. O'Keefe +4 more
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Articular cartilage is a complex tissue maintained by chondrocytes, which undergo metabolic changes as a result of aging, disease, and injury. These changes may hinder tissue maintenance and repair, resulting in accelerated loss of articular surface and leading to end-stage arthritis.
Regis J. O'Keefe +4 more
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Regeneration of Articular Cartilage
2005Loss of articular cartilage from the ends of bones forming diarthrodial joints can be the source of profound pain and disability, and eventually lead to complete degeneration of the joint, necessitating total joint replacement. Until a few years ago, there seemed little hope of treating such defects.
Ramille M. Capito +2 more
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The American Journal of Sports Medicine, 1998
Articular cartilage can tolerate a tremendous amount of intensive and repetitive physical stress. However, it manifests a striking inability to heal even the most minor injury. Both the remarkable functional characteristics and the healing limitations reflect the intricacies of its structure and biology.
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Articular cartilage can tolerate a tremendous amount of intensive and repetitive physical stress. However, it manifests a striking inability to heal even the most minor injury. Both the remarkable functional characteristics and the healing limitations reflect the intricacies of its structure and biology.
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Ultrastructure of articular cartilage
Zeitschrift f�r Zellforschung und Mikroskopische Anatomie, 1959The present paper describes an electron microscopical investigation into the ultrastructure of patellary and femorocondylar articular cartilage from adult guinea pigs, mice and young rats. The following observations were made: 1. The intercellular matrix contains two varieties of collagen fibrils, one being 85 A in diameter and not striated, the ...
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Immunogenicity of Allograft Articular Cartilage
The Journal of Bone & Joint Surgery, 1974Allograft articular cartilage was transplanted between inbred strains of rats and between rabbits. Three forms of allograft were employed: isolated articular chondrocytes, shavings of articular cartilage, and intact articular surfaces. Immunological assessment with the leukocyte migration technique for cell-mediated immunity and Cr51 cytotoxicity for ...
Allan E. Gross, F Langer
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Sports Medicine, Training and Rehabilitation, 1991
The articular cartilage caps the ends of all the long bones and is an essential structure in all diarthrodial Joints. Its homogeneous macroscopic appearance belles its enormous complexity microscopically. It functions as a complicated shock‐absorbing and low friction‐bearing surface.
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The articular cartilage caps the ends of all the long bones and is an essential structure in all diarthrodial Joints. Its homogeneous macroscopic appearance belles its enormous complexity microscopically. It functions as a complicated shock‐absorbing and low friction‐bearing surface.
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Articular Cartilage Bioreactors and Bioprocesses
Tissue Engineering, 2003This review summarizes the major approaches for developing articular cartilage, using bioreactors and mechanical stimuli. Cartilage cells live in an environment heavily influenced by mechanical forces. The development of cartilaginous tissue is dependent on the environment that surrounds it, both in vivo and in vitro. Chondrocytes must be cultured in a
Kyriacos A. Athanasiou, Eric M. Darling
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Towards a synthetic articular cartilage
Journal of Biomaterials Science, Polymer Edition, 1993The physical and morphological properties of articular cartilage have been used as a model for the preparation of hydrogel based synthetic analogues of this complex high water content natural hydrogel. The relatively poor strength and stiffness of simple homogeneous hydrogels have been enhanced by semi-interpenetrating polymer network (semi-IPN ...
Philip H. Corkhill +2 more
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2011
Publisher Summary Cell-based therapies are employed significantly in regenerating the damaged cartilage tissue. One of the therapies is periosteal transplantation in which periosteal flap is used to cover the defects and the defects are repaired and filled after 4 weeks with a hyaline-like cartilage whereas the empty control defect shows ...
Francois Ng kee Kwong +2 more
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Publisher Summary Cell-based therapies are employed significantly in regenerating the damaged cartilage tissue. One of the therapies is periosteal transplantation in which periosteal flap is used to cover the defects and the defects are repaired and filled after 4 weeks with a hyaline-like cartilage whereas the empty control defect shows ...
Francois Ng kee Kwong +2 more
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Articular Cartilage: Can Articular Cartilage be Considered a Smart Material? [PDF]
World Journal of GASTROENTEROLOGY, HEPATOLOGY AND ENDOSCOPY, 2021 Bozena K, Michał S, Zenon P
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